Orally administered docetaxel-loaded chitosan-decorated cationic PLGA nanoparticles for intestinal tumors: formulation, comprehensive in vitro characterization, and release kinetics

Scholarly Works

• Frota Reis, A. V.; de Sousa, A. C. C.; de Freitas, J. V. B.; Arruda, B. R.; Ferreira Lima, R. M.; de Araujo Nobre, A. R.; Holanda Araújo, M. L.; da Silva Júnior, I. J.; Eloy, J. O.; Petrilli, R. Effect of PLGA composition on nanoencapsulation, fluorescence stability and cellular internalization of R-phycoerythrin in colorectal cancer cells. International journal of pharmaceutics 2025, 682, 125966. doi:10.1016/j.ijpharm.2025.125966
• Jiang, Q.; Wang, L.; Si, X.; Cui, H.; Li, J.; Tian, J.; Bao, Y.; Xie, X.; Xu, A.; Sun, Y.; Li, B. An anthocyanins-loaded extracellular vesicles coated with fucoidan nano-delivery system for enhancing dietary defense against inflammation-related colon injury. International journal of biological macromolecules 2025, 318, 144948. doi:10.1016/j.ijbiomac.2025.144948
• Sankar, V.; Selvakumar, R.; Narmadha, R.; Jaishree, V. G. Enhanced therapeutic approach for vaginal candidiasis: chitosan nanoparticulate thermoreversible in situ gels for sustained clotrimazole delivery. 3 Biotech 2025, 15, 71. doi:10.1007/s13205-025-04240-6
• Sathiensathaporn, S.; Solé-Porta, A.; Baowan, D.; Pissuwan, D.; Wongtrakoongate, P.; Roig, A.; Katewongsa, K. P. Nanoencapsulation of vitamin B2 using chitosan-modified poly(lactic-co-glycolic acid) nanoparticles: Synthesis, characterization, and in vitro studies on simulated gastrointestinal stability and delivery. Journal of food science 2024, 90, e17631. doi:10.1111/1750-3841.17631
• Villate, A.; Barreto, G. P.; Nicolás, M. S.; Aizpurua-Olaizola, O.; Olivares, M.; Usobiaga, A. Development, Characterization and In Vitro Gastrointestinal Release of PLGA Nanoparticles Loaded with Full-Spectrum Cannabis Extracts. AAPS PharmSciTech 2024, 25, 120. doi:10.1208/s12249-024-02836-4
• Cassano, R.; Trombino, S.; Curcio, F.; Sole, R.; Calviello, G.; Serini, S. ROS-Responsive PLGA-NPs for Co-Delivery of DTX and DHA for Colon Cancer Treatment. International Journal of Translational Medicine 2024, 4, 262–277. doi:10.3390/ijtm4020016
• Vashishat, A.; Singh, A.; Kurmi, B. D.; Gupta, G. D.; Singh, D. A short appraisal of polylactic-co-glycolic acid based polymer nanotechnology for colon cancer: recent advances and literature evidences. Therapeutic delivery 2023, 14, 459–472. doi:10.4155/tde-2023-0027
• Mesrati, M. H.; Tajudin, A. A.; Masarudin, M. J.; Alamassi, M. N.; Abuhamad, A. Y.; Syahir, A. Hyaluronic acid/chitosan-coated poly (lactic-co-glycolic acid) nanoparticles to deliver single and co-loaded paclitaxel and temozolomide for CD44+oral cancer cells. OpenNano 2023, 12, 100166. doi:10.1016/j.onano.2023.100166
• Ahmad, M. Z.; Pathak, K.; Das, R. J.; Saikia, R.; Sarma, H.; Gogoi, N.; Gogoi, U.; Das, A.; Alasiri, A. S.; Abdel-Wahab, B. A.; Abdullah, M. M. Design and Optimization of Quercetin-Loaded Polymeric Eudragit L-100 Nanoparticles for Anti-diabetic Activity with Improved Oral Delivery: In-Vitro and In-Vivo Evaluation. Journal of Inorganic and Organometallic Polymers and Materials 2023, 33, 2411–2428. doi:10.1007/s10904-023-02694-w

Explore citations to this article at