Antibody-conjugated nanoparticles for target-specific drug delivery of chemotherapeutics

Scholarly Works

• Barattini, C.; Volpe, A.; Gori, D.; Lopez, D.; Ventola, A.; Papa, S.; Montanari, M.; Canonico, B. Early Development of an Innovative Nanoparticle-Based Multimodal Tool for Targeted Drug Delivery: A Step-by-Step Approach. Cells 2025, 14, 670. doi:10.3390/cells14090670
• Guzmán-Sastoque, P.; Rodríguez, C. F.; Monsalve, M. C.; Castellanos, S.; Manrique-Moreno, A.; Reyes, L. H.; Cruz, J. C. Nanotheranostics Revolutionizing Gene Therapy: Emerging Applications in Gene Delivery Enhancement. Journal of Nanotheranostics 2025, 6, 10. doi:10.3390/jnt6020010
• Curry, S. D.; Bower, B. M.; Saemundsson, S. A.; Goodwin, A. P.; Cha, J. N. Binding affinity and transport studies of engineered photocrosslinkable affibody-enzyme-nanoparticle constructs. Nanoscale advances 2025, 7, 2239–2247. doi:10.1039/d4na00823e
• Zhang, D.; Zhang, H.; Yang, Y.; Jin, Y.; Chen, Y.; Wu, C. Advancing tissue analysis: Integrating mass tags with mass spectrometry imaging and immunohistochemistry. Journal of proteomics 2025, 316, 105436. doi:10.1016/j.jprot.2025.105436
• Chen, Q.; Jin, J.; Li, P.; Wang, X.; Wang, Q. Navigating Glioma Complexity: The Role of Abnormal Signaling Pathways in Shaping Future Therapies. Biomedicines 2025, 13, 759. doi:10.3390/biomedicines13030759
• Soni, S.; Megha, K.; Shah, V. B.; Shah, A. C.; Bhatt, S.; Merja, M.; Khadela, A. Unlocking the therapeutic potential of antibody-drug conjugates in targeting molecular biomarkers in non-small cell lung cancer. Journal of the Egyptian National Cancer Institute 2025, 37, 6. doi:10.1186/s43046-025-00264-4
• Asad, S.; Ahl, D.; Suárez-López, Y. D. C.; Erdélyi, M.; Phillipson, M.; Teleki, A. Click Chemistry-Based Bioconjugation of Iron Oxide Nanoparticles. Small (Weinheim an der Bergstrasse, Germany) 2025, 21, e2407883. doi:10.1002/smll.202407883
• Park, W.; Choi, J.; Hwang, J.; Kim, S.; Kim, Y.; Shim, M. K.; Park, W.; Yu, S.; Jung, S.; Yang, Y.; Kweon, D.-H. Apolipoprotein Fusion Enables Spontaneous Functionalization of mRNA Lipid Nanoparticles with Antibody for Targeted Cancer Therapy. ACS nano 2025, 19, 6412–6425. doi:10.1021/acsnano.4c16562
• Thanasi, I. A.; Bouloc, N.; McMahon, C.; Wang, N.; Szijj, P. A.; Butcher, T.; Rochet, L. N. C.; Love, E. A.; Merritt, A.; Baker, J. R.; Chudasama, V. Formation of mono- and dual-labelled antibody fragment conjugates via reversible site-selective disulfide modification and proximity induced lysine reactivity. Chemical science 2025, 16, 2763–2776. doi:10.1039/d4sc06500j
• Bikorimana, J. P.; Farah, R.; Abusarah, J.; Mandl, G. A.; Erregragui, M. A.; Gonçalves, M. P.; Talbot, S.; Matar, P.; Lahrichi, M.; El-Hachem, N.; Rafei, M. Forced intracellular degradation of xenoantigens as a modality for cell-based cancer immunotherapy. iScience 2025, 28, 111957. doi:10.1016/j.isci.2025.111957
• Kapare, H.; Bhosale, M.; Bhole, R. Navigating the future: Advancements in monoclonal antibody nanoparticle therapy for cancer. Journal of Drug Delivery Science and Technology 2025, 104, 106495. doi:10.1016/j.jddst.2024.106495
• Abdelhamid, M. S.; Wadan, A.-H. S.; Saad, H. A.; El-Dakroury, W. A.; Hageen, A. W.; Mohammed, D. H.; Mourad, S.; Mohammed, O. A.; Abdel-Reheim, M. A.; Doghish, A. S. Nanoparticle innovations in targeted cancer therapy: advancements in antibody-drug conjugates. Naunyn-Schmiedeberg's archives of pharmacology 2025. doi:10.1007/s00210-024-03764-7
• Li, K.; Gui, S.; Wang, N.; Li, X.; Zhao, C.; Liu, M.; Zhang, Z. Sequential pH/GSH-responsive stealth nanoparticles for co-delivery of anti-PD-1 antibody and paclitaxel to enhance chemoimmunotherapy of lung cancer. European journal of medicinal chemistry 2025, 285, 117273. doi:10.1016/j.ejmech.2025.117273
• Kumar, B. V.; Shukla, A.; Ahmed, N.; Solanki, K.; Srivastava, N.; Saraf, S. A.; Meher, N. Antibody drug conjugates integrated with lipid nanocarrier for cancer theranostics. Lipid-Drug Conjugates; Elsevier, 2025; pp 333–363. doi:10.1016/b978-0-443-33382-8.00012-1
• Kumari, M.; Piyongsola; Ravi Naik, M.; Singh Rathore, H.; Kumar Shukla, A.; Iqbal Dar, A.; Ravi Kiran, A. V. V. V.; Kumari, K.; Acharya, A.; Thaggikuppe Krishnamurthy, P. Targeted delivery of DAPT using dual antibody functionalized solid lipid nanoparticles for enhanced anti-tumour activity against triple negative breast cancer. International journal of pharmaceutics 2024, 670, 125142. doi:10.1016/j.ijpharm.2024.125142
• Jiang, J.; Kaysar, K.; Pan, Y.; Xia, L.; Li, J. A Zeolitic Imidazolate Framework-Based Antimicrobial Peptide Delivery System with Enhanced Anticancer Activity and Low Systemic Toxicity. Pharmaceutics 2024, 16, 1591. doi:10.3390/pharmaceutics16121591
• Parvin, N.; Mandal, T. K.; Joo, S.-W. The Impact of COVID-19 on RNA Therapeutics: A Surge in Lipid Nanoparticles and Alternative Delivery Systems. Pharmaceutics 2024, 16, 1366. doi:10.3390/pharmaceutics16111366
• Rodponthukwaji, K.; Thongchot, S.; Deureh, S.; Thongkleang, T.; Thaweesuvannasak, M.; Srichan, K.; Srisawat, C.; Thuwajit, P.; Nguyen, K. T.; Tadpetch, K.; Thuwajit, C.; Punnakitikashem, P. Development of cancer-associated fibroblasts-targeting polymeric nanoparticles loaded with 8-O-methylfusarubin for breast cancer treatment. International journal of pharmaceutics: X 2024, 8, 100294. doi:10.1016/j.ijpx.2024.100294
• Velásquez, F.; Frazao, M.; Diez, A.; Villegas, F.; Álvarez-Bidwell, M.; Rivas-Pardo, J. A.; Vallejos-Vidal, E.; Reyes-López, F.; Toro-Ascuy, D.; Ahumada, M.; Reyes-Cerpa, S. Salmon-IgM Functionalized-PLGA Nanosystem for Florfenicol Delivery as an Antimicrobial Strategy against Piscirickettsia salmonis. Nanomaterials (Basel, Switzerland) 2024, 14, 1658. doi:10.3390/nano14201658
• Cong, X.; Zhang, Z.; Li, H.; Yang, Y.-G.; Zhang, Y.; Sun, T. Nanocarriers for targeted drug delivery in the vascular system: focus on endothelium. Journal of nanobiotechnology 2024, 22, 620. doi:10.1186/s12951-024-02892-9

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