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1 article(s) from Egito, Eryvaldo Sócrates T.

Quality by design optimization of microemulsions for topical delivery of Passiflora setacea seed oil

Daniel T. Pereira,
Douglas Dourado,
Danielle T. Freire,
Dayanne L. Porto,
Cícero F. S. Aragão,
Myla L. de Souza,
Guilherme R. S. de Araujo,
Ana Maria Costa,
Wógenes N. Oliveira,
Anne Sapin-Minet,
Éverton N. Alencar and
Eryvaldo Sócrates T. Egito

Beilstein J. Nanotechnol. 2025, 16, 2116–2131, doi:10.3762/bjnano.16.146

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Figure 1: Thermogravimetric analysis, derivative thermogravimetry (DTG), and differential scanning calorimetr...

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Figure 2: Ishikawa (fishbone) diagram illustrating potential sources of variability affecting CQAs in the dev...

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Figure 3: Heatmap of the normalized risk scores (%) illustrating the impact of CMAs and CPPs on each element ...

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Figure 4: Microemulsion systems obtained from Box–Behnken design experimental runs. Each formulation is label...

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Figure 5: Linear regression plots of actual versus predicted values for: (A) hydrodynamic diameter, (B) polyd...

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Figure 6: Surface plots derived from the Box–Behnken design showing the effects of formulation variables on: ...

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Figure 7: Hydrodynamic diameter over a 60 day period for (A) the optimized microemulsion (ME) and (B) the gel...

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Figure 8: pH values of ME and MEgel formulations over a 60 day storage period. Data are presented as mean ± S...

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Figure 9: Thermal analysis of ME and MEgel. (A) Differential thermal and thermogravimetric profiles of the ba...

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Figure 10: Shear stress and viscosity profiles of (A) the base microemulsion, and (B) the gelled microemulsion...

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Figure 11: Mitochondrial activity of (A) RAW 264.7 murine macrophages and (B) HUVECs after 24 h and 48 h of ex...

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Published 20 Nov 2025

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