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Beilstein J. Nanotechnol. 2026, 17, 1142–1158, doi:10.3762/bjnano.17.78
Figure 1: Chemical structures of clinically approved porphyrin-based photosensitizers used in PDT.
Scheme 1: Synthesis of THPP@p(MVCA-BAC) nanoparticles and their GSH-triggered disassembly for ROS generation ...
Figure 2: Optimization of nanoparticle formulation parameters showing hydrodynamic diameter distributions fro...
Figure 3: Data for THPP@p(MVCA-BAC): (A) Hydrodynamic size distribution determined by DLS; three measurements...
Figure 4: (A) Optical characterization of THPP and THPP@p(MVCA-BAC) in PB pH 7.4: UV–vis absorption (black), ...
Figure 5: 1O2 generation monitored via DPBF degradation: (A, B) UV–vis spectral changes of DPBF upon 650 nm i...
Figure 6: (A, B) Cell viability after treatment with p(MVCA-BAC) and THPP@p(MVCA-BAC): (A) in the dark and (B...
Figure 7: Real-time monitoring of the PC-3 cell response to THPP@p(MVCA-BAC) using impedance-based proliferat...
Figure 8: Induction of apoptosis in PC-3 cells incubated with p(MVCA-BAC) and THPP@p(MVCA-BAC), C(THPP) = 2 µ...
Figure 9: Cellular uptake and localization of THPP@p(MVCA-BAC) in PC-3 cells, bright-field, fluorescence, and...
Figure 10: Light-triggered intracellular ROS generation in PC-3 cells, H2DCFDA fluorescence (green) after trea...