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2 article(s) from Lange, Regina

Shape, membrane morphology, and morphodynamic response of metabolically active human mitochondria revealed by scanning ion conductance microscopy

Eric Lieberwirth,
Anja Schaeper,
Regina Lange,
Ingo Barke,
Simone Baltrusch and
Sylvia Speller

Beilstein J. Nanotechnol. 2025, 16, 951–967, doi:10.3762/bjnano.16.73

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Figure 1: Characterisation of isolated mitochondria by fluorescence microscopy. Isolated mitochondria were st...

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Figure 2: Characterisation of isolated mitochondria by Western blot analyses. Detection of specific proteins ...

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Figure 3: False-colour topographies and statistical analyses to illustrate the geometric properties of metabo...

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Figure 4: False-colour topography of a fixed mitochondrion and statistical analysis to illustrate the geometr...

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Figure 5: Measurements illustrating the edge memory effect. (a) Difference image of a larger mitochondrion, 1...

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Figure 6: Measurements illustrating drift phenomena in SPM. (a) Difference image of a fixed mitochondrion, 25...

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Figure 7: Measurements illustrating the intermittency effect, where dashed lines show the location of line pr...

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Figure 8: Schematic illustration of the morphodynamics of the mitochondrial network in cells and their hypoth...

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Figure 9: Mitochondrial network in an intact HeLa cell stained with MTG. Mitochondria (green) interact with s...

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Full Research Paper

Published 30 Jun 2025

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The nanomorphology of cell surfaces of adhered osteoblasts

Christian Voelkner,
Mirco Wendt,
Regina Lange,
Max Ulbrich,
Martina Gruening,
Susanne Staehlke,
Barbara Nebe,
Ingo Barke and
Sylvia Speller

Beilstein J. Nanotechnol. 2021, 12, 242–256, doi:10.3762/bjnano.12.20

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Figure 1: SICM analysis of a fixed MG-63 osteoblastic cell. (a) Overview morphology of the cell on glass afte...

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Figure 2: Living osteoblast cell adhered to glass after 24 h of culturing. (a, e) SICM topography images. The...

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Figure 3: Comparison of living and fixed MG-63 cells by SICM. (a) Osteoblast adhered to glass after fixation ...

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Figure 4: SICM analysis of a fixed cell adhered for 24 h to a 10 nm Au layer. (a) SICM topography of the peri...

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Figure 5: (a) Correlation plot of the relative excess surface (ordinate) and the total adhesion interface are...

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Figure 6: Other membrane features observed by SICM on fixed osteoblastic cells on glass (24 h). (a) Circular ...

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Figure 7: Further membrane features and apparently featureless regions observed by SICM. (a) Pseudo-3D view o...

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Figure 8: Scanning electron microscopy of an MG-63 osteoblast after 3 h of adhesion to titanium. The ruffles ...

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Figure 9: Edge height analysis. (a) Topography of a fixed osteoblast on a 10 nm Au layer on glass with indica...

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Figure 10: Membrane fluctuations of fixed and living MG-63 osteoblastic cells. (a) Local height variations as ...

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Figure 11: Power spectral density of vertical membrane fluctuations of a living osteoblastic cell. The exponen...

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Published 12 Mar 2021

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