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Beilstein J. Nanotechnol. 2025, 16, 740–748, doi:10.3762/bjnano.16.57
Figure 1: The source and treatment of FCS in culture media dictate LNP uptake by HMEC-1 cells. The mean fluor...
Figure 2: Schematic representation of the heat treatment and ThT staining of ApoE. Binding of ThT to misfolde...
Figure 3: Heat-mediated aggregation/denaturation prevents ApoE from binding to LNPs and reduces LNP uptake by...
Figure 4: The uptake of MC3 LNPs is ApoE dependent and is affected by heat inactivation of FCS, while the upt...
Figure 5: Heat inactivation of FCS and endogenous ApoE diminishes the firefly luciferase knockdown efficacy o...