Rapid synthesis of highly monodisperse AgSbS₂ nanocrystals: unveiling multifaceted activities in cancer therapy, antibacterial strategies, and antioxidant defense

• Funda Ulusu,
• Adem Sarilmaz,
• Yakup Ulusu,
• Faruk Ozel and
• Mahmut Kus

Beilstein J. Nanotechnol. 2025, 16, 2105–2115, doi:10.3762/bjnano.16.145

• , Department of Mechanical Engineering, 53020, Rize, Turkey Department of Chemical Engineering, Konya Technical University, Konya, Turkey 10.3762/bjnano.16.145 Abstract Nanocrystals (NCs) of silver antimony sulfide (AgSbS2) in the cubic phase were successfully synthesized using the hot-injection method. This

• effects by efficiently eliminating DPPH activity. This research highlights the potential of AgSbS2 NCs as versatile agents with applications in biomedical and environmental domains, including cancer therapy, antimicrobial strategies, and free radical neutralization. Keywords: AgSbS2 nanocrystals

• , these materials have also been used in various imaging applications for the detection of cancer cells. Ag2Te and Ag2S nanocrystals (NCs) were used in cancer imaging studies by Nieves and colleagues. In this study, computed tomography contrasts changes of NCs injected into mice were examined at 2 and 24

Laser ablation in liquids for shape-tailored synthesis of nanomaterials: status and challenges

• Natalie Tarasenka

Beilstein J. Nanotechnol. 2025, 16, 1963–1997, doi:10.3762/bjnano.16.137

• of NP size and size distribution. As a result, the crucial experimental parameters were determined providing strategies to reduce the formation of large NPs and to produce monodisperse small nanocrystals [1][5]. However, the goal of controlled nanomaterials synthesis by PLAL is still not completely

• nanoparticles, typically those with diameters of only a few nanometres, because their high proportion of surface atoms with low coordination and broken bonds leads to increased surface energy [13]. Furthermore, in assembled nanocrystals, the surface energy can be different in different directions, which induces

• . Manipulation of the structure and concentration of surface groups influence coupling between the interacting nanocrystals and open the pathways for engineering nanostructure shape. As demonstrated in [40], the AgBr nanosheets were only formed if the CTAB concentration exceeds 0.001 M, while at lower

Influence of laser beam profile on morphology and optical properties of silicon nanoparticles formed by laser ablation in liquid

• Natalie Tarasenka,
• Vladislav Kornev,
• Alena Nevar and
• Nikolai Tarasenko

Beilstein J. Nanotechnol. 2025, 16, 1533–1544, doi:10.3762/bjnano.16.108

• of nanocrystals increases with decreasing size due to quantum confinement. Accordingly, the estimated bandgaps for all the prepared colloids was found to be in the range of 1.8–2.2 eV, which is larger than the bandgap of bulk Si (1.12 eV) and can be attributed to the NPs size effects (Figure 6b). The

Laser processing in liquids: insights into nanocolloid generation and thin film integration for energy, photonic, and sensing applications

• Akshana Parameswaran Sreekala,
• Pooja Raveendran Nair,
• Jithin Kundalam Kadavath,
• Bindu Krishnan,
• David Avellaneda Avellaneda,
• M. R. Anantharaman and
• Sadasivan Shaji

Beilstein J. Nanotechnol. 2025, 16, 1428–1498, doi:10.3762/bjnano.16.104

• quenching, and the challenges of oxidation in nanoparticle synthesis. Cost-effective methods for modifying the surface characteristics of Si nanocrystals (Si-ncs) and BaTaOxNy perovskite particles using laser fragmentation are reported in [39] and [40], respectively. In particular, laser fragmentation in

• better after spin coating than drop casting [110]. A functionalization study on SiC nanocrystals was made. SiC–polyvinyl alcohol (PVA) polymeric nanocomposites were manufactured by adding silicon carbide NPs prepared by PLAL to PVA and thin films of the composites were prepared by spin coating on glass

Enhancing the therapeutical potential of metalloantibiotics using nano-based delivery systems

• Alejandro Llamedo,
• Marina Cano,
• Raquel G. Soengas and
• Francisco J. García-Alonso

Beilstein J. Nanotechnol. 2025, 16, 1350–1366, doi:10.3762/bjnano.16.98

• targeted release, coupled with the ability to efficiently deliver drugs to cells like macrophages, make MSiNPs an attractive option for overcoming drug delivery challenges, such as those encountered with bacterial infections [91]. Quantum dots. Quantum dots (QDs) are semiconductor nanocrystals generally

Better together: biomimetic nanomedicines for high performance tumor therapy

• Imran Shair Mohammad,
• Gizem Kursunluoglu,
• Anup Kumar Patel,
• Hafiz Muhammad Ishaq,
• Cansu Umran Tunc,
• Dilek Kanarya,
• Mubashar Rehman,
• Omer Aydin and
• Yin Lifang

Beilstein J. Nanotechnol. 2025, 16, 1246–1276, doi:10.3762/bjnano.16.92

• nanostructures were investigated and successfully used for different tumor targeting and treatment applications [120][121][122][123]. In this respect, drug nanocrystals coated with RBC membrane and modified with a tumor-targeting peptide was successfully used for targeted therapy of glioma [124]. The peptide

Hydrogels and nanogels: effectiveness in dermal applications

• Jéssica da Cruz Ludwig,
• Diana Fortkamp Grigoletto,
• Daniele Fernanda Renzi,
• Wolf-Rainer Abraham,
• Daniel de Paula and
• Najeh Maissar Khalil

Beilstein J. Nanotechnol. 2025, 16, 1216–1233, doi:10.3762/bjnano.16.90

• cellulose nanocrystals poly(ε-caprolactone-co-lactide)-b-poly(ethyleneglycol)-b-poly(ε-caprolactone-co-lactide) [217] or doxorubicin-loaded polydopamine-alginate [219] showed inhibition in tumor growth. Thus, this technique tends to present a great advance in the design methods and in the ease of obtaining

Soft materials nanoarchitectonics: liquid crystals, polymers, gels, biomaterials, and others

• Katsuhiko Ariga

Beilstein J. Nanotechnol. 2025, 16, 1025–1067, doi:10.3762/bjnano.16.77

• involved the sequential organization of a colloidal suspension comprising polyaniline/polystyrene sulfonate and ZIF-8 MOF nanocrystals coated with polyallylamine hydrochloride (Figure 14). This functional electrode was designed to combine two key elements, that is, high surface area and porosity with

Time-resolved probing of laser-induced nanostructuring processes in liquids

• Maximilian Spellauge,
• David Redka,
• Mianzhen Mo,
• Changyong Song,
• Heinz Paul Huber and
• Anton Plech

Beilstein J. Nanotechnol. 2025, 16, 968–1002, doi:10.3762/bjnano.16.74

• Bragg peaks (in wide-angle X-ray scattering (WAXS) geometry) to specifically reconstruct the distribution of crystallinity and lattice strain [74]. In pump–probe configuration, photoinduced strain field oscillations in single Au nanocrystals [75] have been resolved. These studies revealed large-scale NP

Synthesis of biowaste-derived carbon-dot-mediated silver nanoparticles and the evaluation of electrochemical properties for supercapacitor electrodes

• Navya Kumari Tenkayala,
• Chandan Kumar Maity,
• Md Moniruzzaman and
• Subramani Devaraju

Beilstein J. Nanotechnol. 2025, 16, 933–943, doi:10.3762/bjnano.16.71

• phase composition could be classified according to the face-centered cubic structure of silver. The XRD spectrum showed that the formed PG-CDs-AgNPs were nanocrystals, as confirmed by the peaks at 2θ ≈ 28.20°, 32.66°, 38.61°, 46.60°, and 57.86°. These Bragg diffraction peaks are equivalent to the (110

• crystalline nature. The ring-like diffraction suggests the (111) plane. The symmetry in the diffraction spots indicates that the spherical particles possess a high degree of crystallinity. Thus, both the SAED pattern and HRTEM image suggest that the synthesized spherical PG-CDs-AgNPs are nanocrystals

Insights into the electronic and atomic structures of cerium oxide-based ultrathin films and nanostructures using high-brilliance light sources

• Paola Luches and
• Federico Boscherini

Beilstein J. Nanotechnol. 2025, 16, 860–871, doi:10.3762/bjnano.16.65

• + sites within the probed depth. The authors found evidence for electron polaron formation within 0.7 ps, followed by fast decay within a few picoseconds and remnant effects persisting for longer than 1000 ps. In nanocrystals, the holes were found to have longer lifetimes than in single crystals, and they

Supramolecular hydration structure of graphene-based hydrogels: density functional theory, green chemistry and interface application

• Hon Nhien Le,
• Duy Khanh Nguyen,
• Minh Triet Dang,
• Huyen Trinh Nguyen,
• Thi Bang Tam Dao,
• Trung Do Nguyen,
• Chi Nhan Ha Thuc and
• Van Hieu Le

Beilstein J. Nanotechnol. 2025, 16, 806–822, doi:10.3762/bjnano.16.61

• exhibited sharp characteristic peaks of the Zn(OH)2 crystal at 2θ = 20.2°, 20.94°, 25.07°, 27.23°, 27.83°, and 32.97° [40][41][42]. Zinc hydroxide nanocrystals (ZH) were formed on the nanocomposite during the precipitation by alkaline ammonia in the synthesis process (see Methods section). The constituents

Morphology and properties of pyrite nanoparticles obtained by pulsed laser ablation in liquid and thin films for photodetection

• Akshana Parameswaran Sreekala,
• Bindu Krishnan,
• Rene Fabian Cienfuegos Pelaes,
• David Avellaneda Avellaneda,
• Josué Amílcar Aguilar-Martínez and
• Sadasivan Shaji

Beilstein J. Nanotechnol. 2025, 16, 785–805, doi:10.3762/bjnano.16.60

• , which demonstrated a detectivity of 1011 Jones. Phase-pure pyrite nanocrystals produced using a hydrothermal polymer-assisted technique had a broad photoresponse in the UV–vis spectral region, with normalized photocurrents as high as 1 to 100 A·cm–2 when a voltage between 0 and 3 V was applied [69]. In

High-temperature epitaxial growth of tantalum nitride thin films on MgO: structural evolution and potential for SQUID applications

• Michelle Cedillo Rosillo,
• Oscar Contreras López,
• Jesús Antonio Díaz,
• Agustín Conde Gallardo and
• Harvi A. Castillo Cuero

Beilstein J. Nanotechnol. 2025, 16, 690–699, doi:10.3762/bjnano.16.53

• still present (33.8 atom % O), along with tantalum oxynitride. Shi et al. [16] synthesized TaN nanocrystals and reported that the TaN 4f7/2 XPS peak appears at 23.5 eV. Similarly, Bayer and collaborators [17] identified the TaC 4f7/2 XPS peak at 23.3 eV, and Yang et al. [18] reported a photoemission

TiO₂ immobilized on 2D mordenite: effect of hydrolysis conditions on structural, textural, and optical characteristics of the nanocomposites

• Marina G. Shelyapina,
• Rosario Isidro Yocupicio-Gaxiola,
• Gleb A. Valkovsky and
• Vitalii Petranovskii

Beilstein J. Nanotechnol. 2025, 16, 128–140, doi:10.3762/bjnano.16.12

• hierarchical micro- and mesoporosity [1][2][3][4][5][6]. Zeolites with hierarchical porous structures can be synthesized using different strategies [4], for example, aggregation of nanocrystals, use of templates, and creation of mesoporosity by forming pillars between 2D lamellae of zeolites separated by

Comparison of organic and inorganic hole transport layers in double perovskite material-based solar cell

• Deepika K and
• Arjun Singh

Beilstein J. Nanotechnol. 2025, 16, 119–127, doi:10.3762/bjnano.16.11

• transported to ETL and HTL, respectively, without recombining [7]. Ozturk et al. [8] addressed the role of a passivation agent at grain boundaries and the surface of perovskite films, namely, quinary kesterite nanocrystals Cu2NiSn(S,Se)4 (CNTSSe) obtained through a facile hot-casting method. Through

Various CVD-grown ZnO nanostructures for nanodevices and interdisciplinary applications

• The-Long Phan,
• Le Viet Cuong,
• Vu Dinh Lam and
• Ngoc Toan Dang

Beilstein J. Nanotechnol. 2024, 15, 1390–1399, doi:10.3762/bjnano.15.112

• annealing Zn powder under atmospheric pressure conditions, we collected nanocrystals with various morphologies, including rods, pencils, sheets, combs, tetrapods, and multilegs. Raman scattering study reveals that the samples are monophasic with a hexagonal structure, and fall into the P63mc space group

Direct electron beam writing of silver using a β-diketonate precursor: first insights

• Katja Höflich,
• Krzysztof Maćkosz,
• Chinmai S. Jureddy,
• Aleksei Tsarapkin and
• Ivo Utke

Beilstein J. Nanotechnol. 2024, 15, 1117–1124, doi:10.3762/bjnano.15.90

• rectangles. Electron micrographs of deposition results using (hfac)AgPMe3 in a commercial gas injection system and a field-emission microscope. (a) Pillar with smooth side walls and without noticeable halo, (b) dark-field STEM image of the pillar with silver nanocrystals appearing as bright spots with

Recent updates in applications of nanomedicine for the treatment of hepatic fibrosis

• Damai Ria Setyawati,
• Fransiska Christydira Sekaringtyas,
• Riyona Desvy Pratiwi,
• A’liyatur Rosyidah,
• Rohimmahtunnissa Azhar,
• Nunik Gustini,
• Gita Syahputra,
• Idah Rosidah,
• Etik Mardliyati,
• Tarwadi and
• Sjaikhurrizal El Muttaqien

Beilstein J. Nanotechnol. 2024, 15, 1105–1116, doi:10.3762/bjnano.15.89

• , inhibition of profibrogenic cytokine and growth factors secretion, and induction of ECM degradation [70]. A summary of liver-targeted delivery systems is shown in Table 1. Passive and active delivery strategies were combined by Luo and co-workers, who prepared silibinin–human serum albumin nanocrystals [71

• ]. The prepared nanocrystals displayed enhanced solubility and in vivo bioavailability of silibinin, which is known for its low solubility and low permeability. The relatively small silibinin nanocrystals (ca. 60 nm) also could passively extravasate through pores of ca. 100 nm diameter in LSECs before

• targeting activated HSCs. The presence of HSA on the surface of the nanocrystals may facilitate active targeting to activated HSCs via secreted protein acidic and rich in cysteine (SPRAC)-mediated endocytosis. It was reported that the activated HSCs overexpressed SPRAC, which is known as classic albumin

When nanomedicines meet tropical diseases

• Eder Lilia Romero,
• Katrien Van Bocxlaer and
• Fabio Rocha Formiga

Beilstein J. Nanotechnol. 2024, 15, 830–832, doi:10.3762/bjnano.15.69

• , Morilla and collaborators presented a critical review on nanomedicines and Chagas disease, highlighting the potential of oral nanocrystals and parenteral nano-immunostimulants to treat this NTD [3]. Moving to leishmaniases, Verçoza et al. evaluated the therapeutic potential of green superparamagnetic iron

Synthesis of silver–palladium Janus nanoparticles using co-sputtering of independent sources: experimental and theorical study

• Maria J. Martínez-Carreón,
• Francisco Solís-Pomar,
• Abel Fundora,
• Claudio D. Gutiérrez-Lazos,
• Sergio Mejía-Rosales,
• Hector N. Fernández-Escamilla,
• Jonathan Guerrero-Sánchez,
• Manuel F. Meléndrez and
• Eduardo Pérez-Tijerina

Beilstein J. Nanotechnol. 2024, 15, 808–816, doi:10.3762/bjnano.15.67

• –palladium alloyed nanocrystals are currently materials of high interest in electronics, specifically because they can be used in the building of electrodes for multilayer ceramic capacitors, exhibiting better thermal performance than silver nanocrystals, partly, because Pd has a relatively high critical

• melting temperature and, partly, because the appearance of moisture delays the diffusion of silver atoms. The synthesis of AgPd nanocrystals with sizes ranging from 2.46 to 6.65 nm has been reported for applications in the manufacturing of electronic components [6]. Chu et al. [7] synthesized Pd–Ag

Fabrication of nanocrystal forms of ᴅ-cycloserine and their application for transdermal and enteric drug delivery systems

• Hsuan-Ang Tsai,
• Tsai-Miao Shih,
• Theodore Tsai,
• Jhe-Wei Hu,
• Yi-An Lai,
• Jui-Fu Hsiao and
• Guochuan Emil Tsai

Beilstein J. Nanotechnol. 2024, 15, 465–474, doi:10.3762/bjnano.15.42

• warrants further investigation for the development of CNS therapeutics. Nanocrystals play an important role in pharmaceutic design and development. The properties of nanocrystals are remarkably different from their bulk material counterpart, attributed to the large surface-area-to-volume ratio which can

• improve the bioavailability. In this study, for the first time, DCS, a highly water-soluble compound, has formed nanocrystals and this was confirmed by scanning electronic microscopy and X-ray powder diffraction. Furthermore, DCS nanocrystals were applied to several formulations to test their stability

• and then to the in vitro Franz diffusion test with reservoir patch formulation as well as in vivo pharmacokinetics study with enteric capsules. We tested these formulations regarding their nanocrystal physical properties, size effect, and dissolution rate, respectively. We found that DCS nanocrystals

Classification and application of metal-based nanoantioxidants in medicine and healthcare

• Nguyen Nhat Nam,
• Nguyen Khoi Song Tran,
• Tan Tai Nguyen,
• Nguyen Ngoc Trai,
• Nguyen Phuong Thuy,
• Hoang Dang Khoa Do,
• Nhu Hoa Thi Tran and
• Kieu The Loan Trinh

Beilstein J. Nanotechnol. 2024, 15, 396–415, doi:10.3762/bjnano.15.36

• ]. Similarly, GPx-mimicking nanomaterials use two GSH molecules as cofactors to generate redox cycles for H2O2 degradation. In GPx-mimicking V2O5 nanocrystals, H2O2 first binds to the surface of V2O5 converting V=O into V-peroxido intermediates. The V-peroxido intermediates then react with GSH to V−OH

• : (1) nanoliposomes, which are a nanoscale bilayer lipid vesicle [132]; (2) nanocapsules, which consist of an inner aqueous core surrounded by a nontoxic polymeric membrane [133]; (3) solid lipid nanoparticles, which consist of a solid lipid core stabilized by a surfactant [134]; and (4) nanocrystals

Nanomedicines against Chagas disease: a critical review

• Maria Jose Morilla,
• Kajal Ghosal and
• Eder Lilia Romero

Beilstein J. Nanotechnol. 2024, 15, 333–349, doi:10.3762/bjnano.15.30

• that structurally simpler formulations with minimal production cost, such as oral nanocrystals and/or parenteral nano-immunostimulants, have the highest chances of making it to the market to treat CD. Nonetheless, substantive political and economic decisions, key to facing technological challenges, are

• still required regarding a realistic use of nanomedicines effective against CD. Keywords: benznidazole; liposomes; nanocrystals; nanomedicines; nanoparticles; Trypanosoma cruzi; Introduction Nanomedicines are used to solve the problems posed by poor solubility and/or permeability and high toxicity of

• the cumulative dose of BNZ would reduce its toxicity without losing effectiveness [48], BNZ has recently been formulated as nanocrystals (NCs). The solubility of BNZ formulated as nanocrystals prepared by nanoprecipitation using the non-ionic surfactant poloxamer 188 as a stabilizer (BNZ-NC) was

CdSe/ZnS quantum dots as a booster in the active layer of distributed ternary organic photovoltaics

• Gabriela Lewińska,
• Piotr Jeleń,
• Zofia Kucia,
• Maciej Sitarz,
• Łukasz Walczak,
• Bartłomiej Szafraniak,
• Jerzy Sanetra and
• Konstanty W. Marszalek

Beilstein J. Nanotechnol. 2024, 15, 144–156, doi:10.3762/bjnano.15.14

• –COOH groups, they can be easily labeled for chemical and biological applications. Low-molecular-weight organic molecules coat highly luminescent semiconductor nanocrystals. Materials and Methods Thin films, the intended active layers, were fabricated using the spin-coating method. The layers were a