Sensing surface PEGylation with microcantilevers

• Natalija Backmann,
• Natascha Kappeler,
• Thomas Braun,
• François Huber,
• Hans-Peter Lang,
• Christoph Gerber and
• Roderick Y. H. Lim

Beilstein J. Nanotechnol. 2010, 1, 3–13, doi:10.3762/bjnano.1.2

• biotechnology on account of its good solubility in water and low toxicity. Polypeptide drugs and nanoparticles designed for drug delivery exhibit enhanced biocompatibility and proteolytic resistance (e.g., “stealth” particles) when modified with PEG (i.e., PEGylation) [1][2]. PEG-functionalized surfaces are