Silica micro/nanospheres for theranostics: from bimodal MRI and fluorescent imaging probes to cancer therapy

• Shanka Walia and
• Amitabha Acharya

Beilstein J. Nanotechnol. 2015, 6, 546–558, doi:10.3762/bjnano.6.57

• Shanka Walia Amitabha Acharya Biotechnology Division, CSIR - Institute of Himalayan Bioresource Technology (CSIR - IHBT), Post Box No. 6, Palampur (H.P.) 176 061, India 10.3762/bjnano.6.57 Abstract Nano-theranostics offer remarkable potential for future biomedical technology with simultaneous

• ; organic dyes; quantum dots; silica nanospheres; theranostics; Review 1 Introduction In the modern era of medical diagnosis, X-rays have long played a major role in the clinical imaging of anatomical details of disease sites [1]. However, the development of suitable molecular diagnostic systems for

• stages of growth and, thus, plays an integral part in medical diagnosis. All the currently available diagnostic imaging methods have their intrinsic advantages and disadvantages. The combination of multimodal imaging and theranostics will lead to cutting-edge technologies in which the potential of the

Inorganic Janus particles for biomedical applications

• Isabel Schick,
• Steffen Lorenz,
• Dominik Gehrig,
• Stefan Tenzer,
• Wiebke Storck,
• Karl Fischer,
• Dennis Strand,
• Frédéric Laquai and
• Wolfgang Tremel

Beilstein J. Nanotechnol. 2014, 5, 2346–2362, doi:10.3762/bjnano.5.244

• precursors were mixed simultaneously. Janus particles as multimodal contrast agents Recent developments in the field of nanoparticles for biomedical applications have increased the interest in multifunctional nanoparticles for theranostics, a combination of therapy and diagnostics, which was realized with

• theranostics [113]. The analysis of the protein corona of nanoparticles shows that the binding profiles do not reflect the relative protein concentrations of the plasma. Recently, Tenzer et al. showed that there is no direct correlation of the surface charge and the isoelectric point of proteins enriched in