In vitro and in vivo interactions of selected nanoparticles with rodent serum proteins and their consequences in biokinetics

• Wolfgang G. Kreyling,
• Stefanie Fertsch-Gapp,
• Martin Schäffler,
• Blair D. Johnston,
• Nadine Haberl,
• Christian Pfeiffer,
• Jörg Diendorf,
• Carsten Schleh,
• Stephanie Hirn,
• Manuela Semmler-Behnke,
• Matthias Epple and
• Wolfgang J. Parak

Beilstein J. Nanotechnol. 2014, 5, 1699–1711, doi:10.3762/bjnano.5.180

• ; Thbs1: thrombospondin 1; HPX: hemopexin; Apoh: apolipoprotein H; Apob: apolipoprotein B; Serping1: serine (or cysteine) peptidase inhibitor; Apoa1: apolipoprotein A1; C4b: complement component 4b; Hbb-b1: hemoglobin, beta adult major chain; Plg: plasminogen; Cfb: complement factor b; Kng1: kininogen 1

Protein-coated pH-responsive gold nanoparticles: Microwave-assisted synthesis and surface charge-dependent anticancer activity

• Dickson Joseph,
• Nisha Tyagi,
• Christian Geckeler and
• Kurt E.Geckeler

Beilstein J. Nanotechnol. 2014, 5, 1452–1462, doi:10.3762/bjnano.5.158

• remaining proteins are expected to retain their amino acid sequence and not have extensive changes in their properties, such as their intrinsic pH and isoelectric points. Composition of amino acid residues Recent reports suggest that amino acid residues, such as aspartic acid, cysteine, glutamic acid

Mimicking exposures to acute and lifetime concentrations of inhaled silver nanoparticles by two different in vitro approaches

• Fabian Herzog,
• Kateryna Loza,
• Sandor Balog,
• Martin J. D. Clift,
• Matthias Epple,
• Peter Gehr,
• Alke Petri-Fink and
• Barbara Rothen-Rutishauser

Beilstein J. Nanotechnol. 2014, 5, 1357–1370, doi:10.3762/bjnano.5.149

• biological media, it was able to show that the dissolution in chloride-containing media is reduced, probably due to the formation of AgCl. In contrast, glucose has no significant effect. Cysteine as a sulphur-containing molecule can decelerate the dissolution process, possibly by blocking of the NP surface

Manipulation of isolated brain nerve terminals by an external magnetic field using D-mannose-coated γ-Fe₂O₃ nano-sized particles and assessment of their effects on glutamate transport

• Tatiana Borisova,
• Natalia Krisanova,
• Arsenii Borуsov,
• Roman Sivko,
• Ludmila Ostapchenko,
• Michal Babic and
• Daniel Horak

Beilstein J. Nanotechnol. 2014, 5, 778–788, doi:10.3762/bjnano.5.90

• through swelling-activated anion channels, cysteine/glutamate exchange, trans-membrane diffusion and volume-sensitive Cl− channels [19][20][21]. In this set of experiments, the extracellular level and unstimulated release of glutamate from nerve terminals in the presence of D-mannose-coated γ-Fe2O3

Biomolecule-assisted synthesis of carbon nitride and sulfur-doped carbon nitride heterojunction nanosheets: An efficient heterojunction photocatalyst for photoelectrochemical applications

• Hua Bing Tao,
• Hong Bin Yang,
• Jiazang Chen,
• Jianwei Miao and
• Bin Liu

Beilstein J. Nanotechnol. 2014, 5, 770–777, doi:10.3762/bjnano.5.89

• ]. Herein, we employ a biomolecule-assisted (L-cysteine) pyrolysis method to synthesize sulfur-doped carbon nitride (CNS) nanosheets, which can serve as the framework to grow CN to form an all CN-based heterojunction composite. The formation of CN/CNS heterojunctions significantly improves the

• carbon nitride (CNS), 222 mg of L-cysteine was blended with 2 g of melamine in an agate mortar, wherein L-cysteine acts as the sulfur source for sulfur doping. During the pyrolysis process, the –SH functional group in L-cysteine reacts with the amine group in melamine to substitute the N atoms and to

Energy transfer in complexes of water-soluble quantum dots and chlorin e6 molecules in different environments

• Irina V. Martynenko,
• Anna O. Orlova,
• Vladimir G. Maslov,
• Alexander V. Baranov,
• Anatoly V. Fedorov and
• Mikhail Artemyev

Beilstein J. Nanotechnol. 2013, 4, 895–902, doi:10.3762/bjnano.4.101

• quantum dots and Ce6 molecules two methods of QD solubilization were used. In the case of covalent binding the hydrophobic CdSe/ZnS/TOPO QDs with a core diameter of 3.5 nm were initially solubilized by L-cysteine. In the second step, the L-cysteine molecules were replaced with molecules of hydroxy

Apertureless scanning near-field optical microscopy of sparsely labeled tobacco mosaic viruses and the intermediate filament desmin

• Alexander Harder,
• Mareike Dieding,
• Volker Walhorn,
• Sven Degenhard,
• Andreas Brodehl,
• Christina Wege,
• Hendrik Milting and
• Dario Anselmetti

Beilstein J. Nanotechnol. 2013, 4, 510–516, doi:10.3762/bjnano.4.60

• the cantilever tip and dye increase the radiative decay rate and thus enhance the quantum yield [34]. Sample preparation The desmin protein was expressed in E.coli, isolated and purified as reported recently [20]. Desmin monomers expose a single cysteine, which is an ideal anchor for dye attachment

Mapping mechanical properties of organic thin films by force-modulation microscopy in aqueous media

• Jianming Zhang,
• Zehra Parlak,
• Carleen M. Bowers,
• Terrence Oas and
• Stefan Zauscher

Beilstein J. Nanotechnol. 2012, 3, 464–474, doi:10.3762/bjnano.3.53

• thermal evaporator (Kurt Lesker PVD 75), and subsequently cleaned by ozone plasma ashing (Emitech K-1050X). Protein monolayer Five tandem B-domains of staphylococcal protein A were expressed and purified from E. coli. The C-terminus of the terminal protein was modified with cysteine to enable protein

Magnetic nanoparticles for biomedical NMR-based diagnostics

• Huilin Shao,
• Tae-Jong Yoon,
• Monty Liong,
• Ralph Weissleder and
• Hakho Lee

Beilstein J. Nanotechnol. 2010, 1, 142–154, doi:10.3762/bjnano.1.17

• . This sequence served as a linker, binding both an avidin-conjugated CLIO population (via the biotin/avidin interaction) as well as a second CLIO population (via the thiol provided by the terminal cysteine on the peptide) [13]. The subsequent addition of caspase-3 disassembled the aggregates by cleaving