Anticancer efficacy of a supramolecular complex of a 2-diethylaminoethyl–dextran–MMA graft copolymer and paclitaxel used as an artificial enzyme

• Yasuhiko Onishi,
• Yuki Eshita,
• Rui-Cheng Ji,
• Masayasu Onishi,
• Takashi Kobayashi,
• Masaaki Mizuno,
• Jun Yoshida and
• Naoji Kubota

Beilstein J. Nanotechnol. 2014, 5, 2293–2307, doi:10.3762/bjnano.5.238

• micelles carrying a drug, they have been shown to be transported to and act on not only endosomes and lysosomes but also the Golgi body and mitochondria [4]. A block copolymer micelle can be used to deliver a hydrophobic drug as a nanocarrier with water-soluble biological affinity. Knowledge of the