Bacteriorhodopsin–ZnO hybrid as a potential sensing element for low-temperature detection of ethanol vapour

• Saurav Kumar,
• Sudeshna Bagchi,
• Senthil Prasad,
• Anupma Sharma,
• Ritesh Kumar,
• Rishemjit Kaur,
• Jagvir Singh and
• Amol P. Bhondekar

Beilstein J. Nanotechnol. 2016, 7, 501–510, doi:10.3762/bjnano.7.44

• attributed to C–O–C asymmetric stretching, O–H bending, C=C stretching and C–H bending of the retinal chromophore, amino acids and lipids [66]. Further investigation indicates a small change in the amide I vibration spectra (at 1660 cm−1) due to the C=O stretch in the skeleton and amide II vibration spectra

Organized films

• Maurizio Canepa and
• Helmuth Möhwald

Beilstein J. Nanotechnol. 2016, 7, 406–408, doi:10.3762/bjnano.7.35

• molecules such as small amino acids, which allow fundamental and still open issues to be addressed about the subtle interplay between molecule–molecule and molecule–substrate interactions in determining the molecular networking at surfaces [27][28][29]. These few notes introduce this Thematic Series, which

Early breast cancer screening using iron/iron oxide-based nanoplatforms with sub-femtomolar limits of detection

• Dinusha N. Udukala,
• Hongwang Wang,
• Sebastian O. Wendel,
• Aruni P. Malalasekera,
• Thilani N. Samarakoon,
• Asanka S. Yapa,
• Gayani Abayaweera,
• Matthew T. Basel,
• Pamela Maynez,
• Raquel Ortega,
• Yubisela Toledo,
• Leonie Bossmann,
• Colette Robinson,
• Katharine E. Janik,
• Olga B. Koper,
• Ping Li,
• Massoud Motamedi,
• Daniel A. Higgins,
• Gary Gadbury,
• Gaohong Zhu,
• Deryl L. Troyer and
• Stefan H. Bossmann

Beilstein J. Nanotechnol. 2016, 7, 364–373, doi:10.3762/bjnano.7.33

• ://www.lifetein.com/peptide-analysis-tool.html). Essential amino acids of the consensus sequences are bold. Supporting Information Supporting Information File 68: Determination of matrix effects on the observed fluorescence intensities of the nanoplatforms, relative error from 10 repetitive protease measurements

Single pyrimidine discrimination during voltage-driven translocation of osmylated oligodeoxynucleotides via the α-hemolysin nanopore

• Yun Ding and
• Anastassia Kanavarioti

Beilstein J. Nanotechnol. 2016, 7, 91–101, doi:10.3762/bjnano.7.11

• bases by amino acids or by PEGylation [33][34][35], assessing the specific current level sensed by the pore for each possible sequence in order to create a complete data set of current signatures [36], and the use of improved bioinformatic tools [37][38]. Incorporation of a processing enzyme, phi29 DNA

Ultrastructural changes in methicillin-resistant Staphylococcus aureus induced by positively charged silver nanoparticles

• Dulce G. Romero-Urbina,
• Humberto H. Lara,
• J. Jesús Velázquez-Salazar,
• M. Josefina Arellano-Jiménez,
• Eduardo Larios,
• Anand Srinivasan,
• Jose L. Lopez-Ribot and
• Miguel José Yacamán

Beilstein J. Nanotechnol. 2015, 6, 2396–2405, doi:10.3762/bjnano.6.246

• permeability [38]. After penetrating the cell membrane, AgNPs can also alter sulfur-containing amino acids and phosphorus (a main constituent of DNA), inhibiting replication via attaching to the bacterial ribosome [39][40]. The proteomic signatures of AgNP-treated E. coli demonstrated an accumulation of

Green and energy-efficient methods for the production of metallic nanoparticles

• Mitra Naghdi,
• Mehrdad Taheran,
• Satinder K. Brar,
• M. Verma,
• R. Y. Surampalli and
• J. R. Valero

Beilstein J. Nanotechnol. 2015, 6, 2354–2376, doi:10.3762/bjnano.6.243

• their FTIR results, different sugars, amino acids and fatty acids are responsible for the stabilization processes. They also observed that by changing the concentration of precursor, one can obtain NPs with average particle diameter from 7.8 to 4.8 nm [89]. Polyols Shameli et al. used polyethylene

• Ag ions during process [66]. Kumar et al. used amino acid based phenolic compounds as reducer and stabilizer for production of Ag NPs from AgNO3 at room temperature. They stated that amino acids have reactive hydroxyl groups and their structural variations can result in the production of spherical

Au nanoparticle-based sensor for apomorphine detection in plasma

• Chiara Zanchi,
• Andrea Lucotti,
• Matteo Tommasini,
• Sebastiano Trusso,
• Ugo de Grazia,
• Emilio Ciusani and
• Paolo M. Ossi

Beilstein J. Nanotechnol. 2015, 6, 2224–2232, doi:10.3762/bjnano.6.228

• regions where the SERS spectrum of blood plasma does not display any characteristic band. Using the near-infrared excitation at 785 nm, the spectra are dominated by protein bands with broad amide bands at 1650 cm−1 (amide I) and 1250 cm−1 (amide III), and sharp bands due to aromatic amino acids at 1004 cm

The role of low-energy electrons in focused electron beam induced deposition: four case studies of representative precursors

• Rachel M. Thorman,
• Ragesh Kumar T. P.,
• D. Howard Fairbrother and
• Oddur Ingólfsson

Beilstein J. Nanotechnol. 2015, 6, 1904–1926, doi:10.3762/bjnano.6.194

• attachment leads to the formation of neutral HF, which in turn releases the 5.9 eV HF BDE [37] and promotes further fragmentation of the parent molecule. This is also observed for other molecules such as the amino acids glycine [38] and valine [39], and hexafluoroacetone azine [40], wherein the formation of

Atomic force microscopy as analytical tool to study physico-mechanical properties of intestinal cells

• Christa Schimpel,
• Oliver Werzer,
• Eleonore Fröhlich,
• Gerd Leitinger,
• Markus Absenger-Novak,
• Birgit Teubl,
• Andreas Zimmer and
• Eva Roblegg

Beilstein J. Nanotechnol. 2015, 6, 1457–1466, doi:10.3762/bjnano.6.151

• University of Graz, Austria) and were grown in RPMI 1640 medium supplemented with 10% fetal bovine serum (FBS) (Invitrogen GmbH, Darmstadt, Germany), 1% non-essential amino acids (NEAA) (Invitrogen GmbH, Darmstadt, Germany), 1% L-glutamine (Invitrogen GmbH, Darmstadt, Germany) and 1% penicillin and

Peptide-equipped tobacco mosaic virus templates for selective and controllable biomineral deposition

• Klara Altintoprak,
• Axel Seidenstücker,
• Alexander Welle,
• Sabine Eiben,
• Petia Atanasova,
• Nina Stitz,
• Alfred Plettl,
• Joachim Bill,
• Hartmut Gliemann,
• Holger Jeske,
• Dirk Rothenstein,
• Fania Geiger and
• Christina Wege

Beilstein J. Nanotechnol. 2015, 6, 1399–1412, doi:10.3762/bjnano.6.145

• [53][54], or into particles fashioned evenly with mixtures of two or more functional groups at predefined ratios [51]. To vary and control the deposition of inorganic minerals on TMV templates, extensive modifications of the surface amino acids are desirable. They enable defined alterations of the

• modification of the TMV–CP sequence is, however, limited in view of the extent of alteration tolerated by virus particles upon their multiplication in plants, regarding number and composition of exchanged or inserted amino acids. In addition, high-throughput screening of different surface-expressed peptides is

• tetraethylorthosilicate, TEOS) in alcohol-containing media (see Figure 1 for the mechanistic scheme). Obviously, the viral coating (which exhibits patches of both positively and negatively charged amino acids in nanometric vicinity to each other) is prone to silica deposition by itself. Concomitant with silicification

Natural and artificial binders of polyriboadenylic acid and their effect on RNA structure

• Giovanni N. Roviello,
• Domenica Musumeci,
• Valentina Roviello,
• Marina Pirtskhalava,
• Alexander Egoyan and
• Merab Mirtskhulava

Beilstein J. Nanotechnol. 2015, 6, 1338–1347, doi:10.3762/bjnano.6.138

• structures of adducts formed between amino acids and europium metal ions, was investigated for the first time. In particular, a L-valine-europium complex (Figure 12) proved to be able to bind both the DNA and RNA molecules studied by the authors. Interestingly, this complex was able to induce self-structure

Fulleropeptide esters as potential self-assembled antioxidants

• Mira S. Bjelaković,
• Tatjana J. Kop,
• Jelena Đorđević and
• Dragana R. Milić

Beilstein J. Nanotechnol. 2015, 6, 1065–1071, doi:10.3762/bjnano.6.107

• -assembly has been observed. Here, cryo-transmission electron microscopy [14] and SEM [15] experiments on aqueous solutions of fullerene-based amino acids and peptides confirmed their strong aggregation behavior and formation of spherical and ellipsoidal clusters. In the area of biological applications, a

• described the synthesis and provided a thorough spectral characterization of a series of fulleropeptide tert-butyl esters (2–12, Figure 1) consisting of two aliphatic amino acids, γ-aminobutyric acid (GABA) and glycine (Gly), using fulleropyrrolidinic ester 1 as a starting compound. In continuation of our

Morphology control of zinc oxide films via polysaccharide-mediated, low temperature, chemical bath deposition

• Florian Waltz,
• Hans-Christoph Schwarz,
• Andreas M. Schneider,
• Stefanie Eiden and
• Peter Behrens

Beilstein J. Nanotechnol. 2015, 6, 799–808, doi:10.3762/bjnano.6.83

• (malate) [36], ascorbate [37], diaminopropane [38], hexadecyl(trimethyl)azanium bromide (CTAB) [39], and block copolymers [40] have been used for this purpose, in addition to naturally occurring amino acids and peptides [41], which have already been successfully applied in this respect. We recently

Functionalization of α-synuclein fibrils

• Simona Povilonienė,
• Vida Časaitė,
• Virginijus Bukauskas,
• Arūnas Šetkus,
• Juozas Staniulis and
• Rolandas Meškys

Beilstein J. Nanotechnol. 2015, 6, 124–133, doi:10.3762/bjnano.6.12

• ]. α-Syn has an unfolded C-terminal region and the NAC region (amino acids 61–95) that is responsible for aggregation. It was also demonstrated that the C-terminal is very important in the oligomerization process [47] and has a chaperone-like activity [11]. Therefore, a α-SynC141 mutant with one

Chemoselective silicification of synthetic peptides and polyamines

• Maryna Abacilar,
• Fabian Daus and
• Armin Geyer

Beilstein J. Nanotechnol. 2015, 6, 103–110, doi:10.3762/bjnano.6.10

• by 1H NMR. The polyamines 1, 2, and 3 have increasing numbers of 4, 5 and 11 basic nitrogens. Peptide 4 is a simplified sequence derived from the silaffins and bears 6 primary amines. Amino acids are characterized by the one-letter code (S Serin, K Lysin, G Glycin, Y Tyrosine). Toxine 5 is the

Synthesis of boron nitride nanotubes and their applications

• Saban Kalay,
• Zehra Yilmaz,
• Ozlem Sen,
• Melis Emanet,
• Emine Kazanc and
• Mustafa Çulha

Beilstein J. Nanotechnol. 2015, 6, 84–102, doi:10.3762/bjnano.6.9

• interaction with the surface of the BNNTs. This study provides a deeper understanding into the nature of the interactions of amino acids (and perhaps similar molecules) with surface of the BNNTs [68]. The interaction of a peptide, HWSAWWIRSNQS, with BNNTs was studied using AFM [69]. It was found that the

Coating with luminal gut-constituents alters adherence of nanoparticles to intestinal epithelial cells

• Heike Sinnecker,
• Katrin Ramaker and
• Andreas Frey

Beilstein J. Nanotechnol. 2014, 5, 2308–2315, doi:10.3762/bjnano.5.239

• acids representative for an alimentary peptide source, we noticed that this seemed to have no substantial effect on the adherence of NPs to the cells, only with the 20 nm NPs slightly higher fluorescence intensities were measured (Figure 2A). Individual peptides and amino acids of this extract do

• showed that the decrease in fluorescence at the cell surface was not associated with an increased fluorescence inside the cells, indicating that the protein coat had not led to an enhanced NP uptake by the cells. When analyzing the effect of NP treatment with meat extract, a mixture of peptides and amino

Biopolymer colloids for controlling and templating inorganic synthesis

• Laura C. Preiss,
• Katharina Landfester and
• Rafael Muñoz-Espí

Beilstein J. Nanotechnol. 2014, 5, 2129–2138, doi:10.3762/bjnano.5.222

• find starch [13][14], different cellulose derivatives [15], dextran [16], pectin [17], alginate [18], and poly(amino acids) or proteins [19][20][21][22][23][24][25][26][27][28][29]. Researchers in the biomineralization field very often extract proteins from biological matter and use them for the ex

• to the surface of colloidal particles. In this sense, Krattiger et al. [44] reported the morphogenesis of CaCO3 and DL-alanine crystals in the presence of polystyrene beads functionalized with synthetic peptides with different amino acids and oligopeptides. B. Biopolymers as “supports” B1. Molecular

Real-time monitoring of calcium carbonate and cationic peptide deposition on carboxylate-SAM using a microfluidic SAW biosensor

• Anna Pohl and
• Ingrid M. Weiss

Beilstein J. Nanotechnol. 2014, 5, 1823–1835, doi:10.3762/bjnano.5.193

• -lysine core (N-EEKKKKKES-C vs N-AKKKKKAS-C) interact with carboxylates on the SAM-biosensor chip surface in a different way. The presence of the glutamic acid residues stabilizes the mode of interaction with the charged surface. When lysine residues are flanked by neutral amino acids, the interaction

Donor–acceptor graphene-based hybrid materials facilitating photo-induced electron-transfer reactions

• Anastasios Stergiou,
• Georgia Pagona and
• Nikos Tagmatarchis

Beilstein J. Nanotechnol. 2014, 5, 1580–1589, doi:10.3762/bjnano.5.170

• to introduce fused pyrrolidine rings into the skeleton of graphene [38]. Azomethine ylides are organic 1,3-dipoles possessing a carbanion next to an iminium ion and can be readily produced upon decarboxylation of the iminium salts derived from the condensation of α-amino acids with aldehydes or

Synthesis of hydrophobic photoluminescent carbon nanodots by using L-tyrosine and citric acid through a thermal oxidation route

• Venkatesh Gude

Beilstein J. Nanotechnol. 2014, 5, 1513–1522, doi:10.3762/bjnano.5.164

• ]. The as-prepared CNDs are hydrophilic in nature. There are some synthetic routes by using citric acid and some surface passivating agents like L-lysine [15], ethanolamine [20], betaine [21] to obtain hydrophilic CNDs through thermal oxidation in air. Amino acids like histidine, arginine, threonine, and

Protein-coated pH-responsive gold nanoparticles: Microwave-assisted synthesis and surface charge-dependent anticancer activity

• Dickson Joseph,
• Nisha Tyagi,
• Christian Geckeler and
• Kurt E.Geckeler

Beilstein J. Nanotechnol. 2014, 5, 1452–1462, doi:10.3762/bjnano.5.158

• . Whereas at acidic, neutral and basic pH conditions, different colored dispersions were observed, and detailed studies on their size and shape are in progress. Hence, varying the pH of the protein solution modifies the structural confirmation of the protein, which alters the native state of the amino acids

• , respectively. Based on these results, we speculate that there were no major structural deformations for LYS and HIS. However, OVA and BSA, which are globular proteins, may have unpacked into a linear chain, thereby exposing other amino acids that could absorb in the UV region and thus increasing the UV

• amino acids could be responsible for the formation of AuNPs. The percentage of hydrophobic residues (HR), aromatic residues (ArR), polar residues (PR), acidic residues (AcR), basic residues (BR), and charged residues (CR) contained in each protein was calculated and compared with the intensities of the

Nanodiamond-DGEA peptide conjugates for enhanced delivery of doxorubicin to prostate cancer

• Amanee D Salaam,
• Patrick Hwang,
• Roberus McIntosh,
• Hadiyah N Green,
• Ho-Wook Jun and
• Derrick Dean

Beilstein J. Nanotechnol. 2014, 5, 937–945, doi:10.3762/bjnano.5.107

• , which was mainly due to the covalent bonding of the peptide to the surface. FTIR confirmed that the layer was DGEA as several characteristic peaks for DGEA were represented in the ND-DGEA spectrum (Figure 3). Particularly, there were peaks due to C–N stretching in primary or secondary amines of amino

• acids between 1130 and 1390 cm–1, carbonyl stretching in the amide I bonds (1655 cm–1), and NH bending of the primary amine (1544 cm–1). There was also a broadening of the 1544 cm–1 peak (amide II), signifying successful conjugation as additional amide bonds were formed between the carboxyl groups on

Controlling mechanical properties of bio-inspired hydrogels by modulating nano-scale, inter-polymeric junctions

• Seonki Hong,
• Hyukjin Lee and
• Haeshin Lee

Beilstein J. Nanotechnol. 2014, 5, 887–894, doi:10.3762/bjnano.5.101

• quinones. For mussel adhesives, DOPAquinone is formed by oxidation of a catecholic amino acid, 3,4-dihydroxy-L-phenylalanine (DOPA). Subsequently, DOPAquinone rapidly reacts with basic amino acids, such as lysine and/or histidine, forming covalent adducts of DOPA-DOPA, lysyl-DOPA, and/or histeinyl-DOPA [7

Morphological characterization of fullerene–androsterone conjugates

• Alberto Ruiz,
• Margarita Suárez,
• Nazario Martin,
• Fernando Albericio and
• Hortensia Rodríguez

Beilstein J. Nanotechnol. 2014, 5, 374–379, doi:10.3762/bjnano.5.43

• suitably functionalized fullerene derivatives with physical and biological properties interesting for biomedicine and materials science [2]. The covalent linkage of C60 to moieties, such as porphyrins [3], anionic polymethine cyanine [4], and other bioactive molecules such as amino acids [5], peptides [6