PLGA nanoparticles as a platform for vitamin D-based cancer therapy

• Maria J. Ramalho,
• Joana A. Loureiro,
• Bárbara Gomes,
• Manuela F. Frasco,
• Manuel A. N. Coelho and
• M. Carmo Pereira

Beilstein J. Nanotechnol. 2015, 6, 1306–1318, doi:10.3762/bjnano.6.135

• to work as cytoplasmic delivery vehicles. Also, because calcitriol has a short half-life, its entrapment in PLGA NPs allows vitamin protection, sustained and controlled delivery, thus avoiding drug degradation and inactivation. The sustained and controlled release of the prepared PLGA NPs explains

Silica micro/nanospheres for theranostics: from bimodal MRI and fluorescent imaging probes to cancer therapy

• Shanka Walia and
• Amitabha Acharya

Beilstein J. Nanotechnol. 2015, 6, 546–558, doi:10.3762/bjnano.6.57

• materials [8], for controlled delivery [9], and in biotechnology for the controlled release of biomolecules such as small drugs [10], therapeutic proteins [11], antibiotics [12], and antibodies [13]. In MRI, the relative difference of the signal intensity between two adjoining tissues can be improved by

Pulmonary surfactant augments cytotoxicity of silica nanoparticles: Studies on an in vitro air–blood barrier model

• Jennifer Y. Kasper,
• Lisa Feiden,
• Maria I. Hermanns,
• Christoph Bantz,
• Michael Maskos,
• Ronald E. Unger and
• C. James Kirkpatrick

Beilstein J. Nanotechnol. 2015, 6, 517–528, doi:10.3762/bjnano.6.54

• as drug delivery vehicles for the controlled release of drugs [28][29]. However, others have shown that the toxicity of functionalized NPs is cell type-dependent, as they were able to demonstrate that carboxyl-functionalized NPs caused toxic effects in a macrophage cell line, RAW264.7, and a human

Release behaviour and toxicity evaluation of levodopa from carboxylated single-walled carbon nanotubes

• Julia M. Tan,
• Jhi Biau Foo,
• Sharida Fakurazi and
• Mohd Zobir Hussein

Beilstein J. Nanotechnol. 2015, 6, 243–253, doi:10.3762/bjnano.6.23

• nanohybrid possessed favourable sustained and controlled release properties as a drug carrier. In vitro bioassay PC12 cell lines PC12 is one of the most widely applied neuronal cell lines and can be used as a model to study secretory activity and catecholamine metabolism and regulation. In this study, we

• controlled release properties of the material using a Lambda 35 spectrophotometer (Perkin Elmer, Boston, MA). In order to study the functional groups present in the materials, Fourier transform infrared (FTIR) spectra of the samples were recorded over the range of 4000–500 cm−1 on a 1752X FTIR (Perkin Elmer

Microfluidic anodization of aluminum films for the fabrication of nanoporous lipid bilayer support structures

• Jaydeep Bhattacharya,
• Alexandre Kisner,
• Andreas Offenhäusser and
• Bernhard Wolfrum

Beilstein J. Nanotechnol. 2011, 2, 104–109, doi:10.3762/bjnano.2.12

• as template structures in nanofabrication technology [9][10][11][12][13][14][15][16][17][18][19][20] to their direct use as functional interfaces for controlled release of molecules [21][22][23], co-culture development [24], or biosensing [25]. For example, Steinem et al. have demonstrated the