Comparison of the interactions of daunorubicin in a free form and attached to single-walled carbon nanotubes with model lipid membranes

• Dorota Matyszewska

Beilstein J. Nanotechnol. 2016, 7, 524–532, doi:10.3762/bjnano.7.46

• transport daunorubicin to cancer cells [5]. Drug delivery systems are aimed at providing enhanced transport of therapeutic agents directly to the targeted organs and tissues, which enables the elimination or significant decrease in the side effects of a drug. One of the most common type of drug nanocarriers

Predicting cytotoxicity of PAMAM dendrimers using molecular descriptors

• David E. Jones,
• Hamidreza Ghandehari and
• Julio C. Facelli

Beilstein J. Nanotechnol. 2015, 6, 1886–1896, doi:10.3762/bjnano.6.192

• acceptor count. The third analysis used only molecular descriptors selected by expert advice: molecular weight, atom count, pI, and molecular polarizability. In this paper we refer to selected by expert advice as the properties that an experienced researcher in nanocarriers, Dr. Ghandehari, expected to be

PLGA nanoparticles as a platform for vitamin D-based cancer therapy

• Maria J. Ramalho,
• Joana A. Loureiro,
• Bárbara Gomes,
• Manuela F. Frasco,
• Manuel A. N. Coelho and
• M. Carmo Pereira

Beilstein J. Nanotechnol. 2015, 6, 1306–1318, doi:10.3762/bjnano.6.135

• nanocarriers for vitamin D3 delivery towards cancer treatment. Vitamin D3 vectorisation to guarantee specific action on malignant cells that avoids side effects such as hypercalcemia has been proposed. Nguyen et al. developed a formulation based on poly(vinyl neodecanoate-crosslinked-ethyleneglycol

• NPs were prepared as nanocarriers, and for the purpose of formulating and characterizing the designed system, the inactive form of vitamin D3, cholecalciferol, was also used as drug model along with calcitriol. We evaluated the effect of calcitriol-loaded PLGA NPs on normal and tumor cells in terms of

Hematopoietic and mesenchymal stem cells: polymeric nanoparticle uptake and lineage differentiation

• Ivonne Brüstle,
• Thomas Simmet,
• Gerd Ulrich Nienhaus,
• Katharina Landfester and
• Volker Mailänder

Beilstein J. Nanotechnol. 2015, 6, 383–395, doi:10.3762/bjnano.6.38

• therapy and nanoparticles promises to enhance the effect of cellular therapies by using nanocarriers as drug delivery devices to guide the further differentiation or homing of stem cells. The impact of nanoparticles on primary cell types remains much more elusive as most groups study the nanoparticle–cell

Release behaviour and toxicity evaluation of levodopa from carboxylated single-walled carbon nanotubes

• Julia M. Tan,
• Jhi Biau Foo,
• Sharida Fakurazi and
• Mohd Zobir Hussein

Beilstein J. Nanotechnol. 2015, 6, 243–253, doi:10.3762/bjnano.6.23

• , 43400 UPM Serdang, Selangor, Malaysia 10.3762/bjnano.6.23 Abstract This work explores the potential use of commercially obtained, carboxylated, single-walled carbon nanotubes (SWCNT–COOH) as nanocarriers for the antiparkinson drug, levodopa (LD). The resulting nanohybrid was characterized using

Synthesis of boron nitride nanotubes and their applications

• Saban Kalay,
• Zehra Yilmaz,
• Ozlem Sen,
• Melis Emanet,
• Emine Kazanc and
• Mustafa Çulha

Beilstein J. Nanotechnol. 2015, 6, 84–102, doi:10.3762/bjnano.6.9

• the BNNTs via a targeting protein could generate smart and selective nanocarriers to be used in nanomedicine [67]. Physical modifications For these types of modifications, weak interactions such as π–π, hydrophobic, and van der Waals forces are utilized to coat the BNNTs with mostly a polymeric

Nanoencapsulation of ultra-small superparamagnetic particles of iron oxide into human serum albumin nanoparticles

• Matthias G. Wacker,
• Mahmut Altinok,
• Stephan Urfels and
• Johann Bauer

Beilstein J. Nanotechnol. 2014, 5, 2259–2266, doi:10.3762/bjnano.5.235

• the past decades, nanocarriers have been utilized for a variety of different applications. In the area of pharmaceuticals these versatile drug delivery devices enabled the directed transport of drug substances to specific tissues after modification of the particle surface with drug targeting ligands

• the present study, nanoparticles consisting of HSA were formed by ethanolic desolvation [9]. These nanocarriers were used matrix system for the encapsulation of USPIO. USPIO have been efficiently applied as contrast agents for magnetic resonance imaging and allow the tracking of nanoparticles in vivo

• [10][11]. Nanocarriers of this size range have been modified by adsorptive binding or incorporation of drug substances earlier [12][13][14]. Unspecific interactions with the matrix material enabled the binding of drugs such as obidoxime [13], or the binding of hydrophilic complexes of poorly soluble

Optimizing the synthesis of CdS/ZnS core/shell semiconductor nanocrystals for bioimaging applications

• Li-wei Liu,
• Si-yi Hu,
• Ying Pan,
• Jia-qi Zhang,
• Yue-shu Feng and
• Xi-he Zhang

Beilstein J. Nanotechnol. 2014, 5, 919–926, doi:10.3762/bjnano.5.105

• biocompatible polymer nanocarriers for in vivo studies there are Pluronic F127 triblock-copolymer micelle nanoparticles [20][21]. They can serve as a candidate for therapeutic and biomedical applications in vitro and in vivo. A particular material for QDs, CdS, is an important direct-band semiconductor with a

Plasma-assisted synthesis and high-resolution characterization of anisotropic elemental and bimetallic core–shell magnetic nanoparticles

• M. Hennes,
• A. Lotnyk and
• S. G. Mayr

Beilstein J. Nanotechnol. 2014, 5, 466–475, doi:10.3762/bjnano.5.54

• as powerful nanotools in many areas of biology, biophysics and medicine [1]. Possible applications include their use as contrast agents for cell tracking via magnetic resonance imaging (MRI) [2], as colloidal mediators in cancer therapy (hyperthermia) [3] or as nanocarriers for targeted drug delivery