Large-scale analysis of high-speed atomic force microscopy data sets using adaptive image processing

• Blake W. Erickson,
• Séverine Coquoz,
• Jonathan D. Adams,
• Daniel J. Burns and
• Georg E. Fantner

Beilstein J. Nanotechnol. 2012, 3, 747–758, doi:10.3762/bjnano.3.84

• obtain a true representation of the sample and its changes over time. This paper presents an automated, adaptive algorithm for the required processing of AFM images. The algorithm adaptively corrects for both common one-dimensional distortions as well as the most common two-dimensional distortions. This

• . This amount of data creates a significant increase in the amount of image processing needed to extract the true sample topography, which can no longer be performed by the user on an image-by-image basis [15][17]. In HS-AFM, there is a real need for an automated processing routine that optimizes the

• [30][31]. Automated, AFM quality-control check in semiconductors and other nanotechnologies [32][33][34] also creates large data sets, which would also benefit from reliable automated image processing. In order to automate the image processing, it is important to define a metric by which the success

Friction and durability of virgin and damaged skin with and without skin cream treatment using atomic force microscopy

• Bharat Bhushan,
• Si Chen and
• Shirong Ge

Beilstein J. Nanotechnol. 2012, 3, 731–746, doi:10.3762/bjnano.3.83

• reciprocating tribometer with a velocity 1 mm/s and at a normal load of 50 mN for 3000 cycles. Contact-angle measurements The apparent contact angles were measured for various samples. Measurements were made with a Rame-Hart automated goniometer model 290-F4, where 5 μL water droplets were deposited onto the

Combining nanoscale manipulation with macroscale relocation of single quantum dots

• Francesca Paola Quacquarelli,
• Richard A. J. Woolley,
• Martin Humphry,
• Jasbiner Chauhan,
• Philip J. Moriarty and
• Ashley Cadby

Beilstein J. Nanotechnol. 2012, 3, 324–328, doi:10.3762/bjnano.3.36

• experiments on a single particle. Automated nanoparticle manipulation and imaging routines have been developed so as to facilitate the rapid assembly of specific nanoparticle arrangements. Keywords: automation; nanoscale manipulation; nanotechnology; quantum dots; single molecule spectroscopy; Introduction

• [13]. The gold nanoparticle was shown to dramatically quench the optical lifetime of the QD and to completely suppress its blinking. Experimental In this work, we position a single fluorophore, a CdSe QD, with nanometre precision on a macroscopic registration template, using automated atomic force

Distinction of nucleobases – a tip-enhanced Raman approach

• Regina Treffer,
• Xiumei Lin,
• Elena Bailo,
• Tanja Deckert-Gaudig and
• Volker Deckert

Beilstein J. Nanotechnol. 2011, 2, 628–637, doi:10.3762/bjnano.2.66

• first sequencing methods were published in 1977 by Maxam and Gilbert [1], and Sanger et al. [2]. Since then the sequencing technology has been refined and automated, and current advances show a tendency towards single-molecule sequencing, which eventually results in the development of sequencing systems

Self-organizing bioinspired oligothiophene–oligopeptide hybrids

• Alexey K. Shaytan,
• Eva-Kathrin Schillinger,
• Elena Mena-Osteritz,
• Sylvia Schmid,
• Pavel G. Khalatur,
• Peter Bäuerle and
• Alexei R. Khokhlov

Beilstein J. Nanotechnol. 2011, 2, 525–544, doi:10.3762/bjnano.2.57

• deprotection conditions, the switch ester segment is preserved at low pH. Reestablishment of the native α-amide peptide backbone can be achieved by an increase in the pH to neutral or even slightly basic conditions. The peptide segment was obtained by a semi-automated solid-phase supported peptide synthesis