Beilstein J. Nanotechnol.2014,5, 778–788, doi:10.3762/bjnano.5.90
level, nanoparticles can pass through the plasma membrane of the cells by means of endocytosis [27]. Opposite point of view argues that uptake of nanoparticles into the cells does not occur by endocytic processes, but rather by diffusion or adhesive interactions [28].
In this study, we have presented a
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Figure 1:
Transmission electron micrographs of (a) neat and (b) D-mannose-coated γ-Fe2O3 nanoparticles.
Beilstein J. Nanotechnol.2014,5, 313–322, doi:10.3762/bjnano.5.35
the cells through an endocytosis pathway (Supporting Information File 1, Figure S5). Calculated image ratio values, R, from the fluorescence microscope images show that the NP formulation produces a higher intracellular fluorescence intensity (R = 3.75 ± 0.54) (mean ± SD) than the free dye (R = 2.89
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Figure 1:
Subcellular localization of free IR820 (A) and IR820-PGMD NPs (B) in SKOV-3 after 24-hour incubatio...