Magnetic nanoparticles for biomedical NMR-based diagnostics

• Huilin Shao,
• Tae-Jong Yoon,
• Monty Liong,
• Ralph Weissleder and
• Hakho Lee

Beilstein J. Nanotechnol. 2010, 1, 142–154, doi:10.3762/bjnano.1.17

• spontaneous aggregation, which could mimic target-induced clustering; 3) have high magnetization and transverse relaxivity (r2) to induce pronounced T2 changes; and 4) have good surface chemistry to simplify conjugational procedures for attaching affinity molecules, such as antibodies and peptides. The MNPs