Gold nanoparticle-decorated reduced graphene oxide as a highly effective catalyst for the selective α,β-dehydrogenation of N-alkyl-4-piperidones

• Brenda Flore Kenyim,
• Mihir Tzalis,
• Marilyn Kaul,
• Robert Oestreich,
• Aysenur Limon,
• Chancellin Pecheu Nkepdep and
• Christoph Janiak

Beilstein J. Nanotechnol. 2026, 17, 218–238, doi:10.3762/bjnano.17.15

• the dehydrogenation of β-N-substituted saturated ketones and other fine chemical applications. Keywords: oxidative dehydrogenation; reduced graphene oxide; supported gold nanoparticles; β-N-substituted ketones; Introduction The properties related to the high surface area of matter at the nanometric

• - compared to N-methyl-4-piperidone. This behavior is consistent with the increased steric bulk, which make the α-hydrogen abstraction step more difficult. The observed catalytic trends further confirm the robustness and adaptability of the Au/rGO catalysts for ODH of structurally related β-N-substituted

• ketones. The corresponding catalytic data and product characterization have been included in Supporting Information File 1. As shown in Table 1, catalysts with CB as support demonstrated lower conversion and yields, while AuNPs supported on AC and rGO achieved nearly complete or complete conversion of the