Synthesis of carbon dot-mediated gold nanostructures: experimental and quantum chemical insights into turn-on fluorescence sensing of N-acetylcysteine

• Thuy-Huong Nguyen,
• Van-Nghia Nguyen,
• Ha Thi Thu Nguyen,
• Ha Ngoc Nguyen,
• Anh Duc Nguyen,
• Tuyen Viet Nguyen and
• Truong Xuan Nguyen

Beilstein J. Nanotechnol. 2026, 17, 1103–1116, doi:10.3762/bjnano.17.75

• fluorescence could be efficiently restored upon the addition of N-acetylcysteine (NAC), enabling the development of an “off-on” fluorescent sensing platform. The sensing mechanism was systematically elucidated through a combination of spectroscopic studies and density functional theory calculations, revealing

• pharmaceutical monitoring. Keywords: fluorescence; gold nanoparticles; green synthesis; N-acetylcysteine; nitrogen-doped carbon dots; Introduction N-acetylcysteine (NAC) has been widely employed for over four decades as an antidote in the treatment of paracetamol (acetaminophen) overdose [1][2][3] and as a

• corresponding fluorescence recovery (ΔI) was compared to determine the optimal solvent composition. Based on these experiments, a water/DMF mixture containing 25% (v/v) DMF was selected and used for all subsequent fluorescence sensing experiments. Assay of N-acetylcysteine Fresh standard NAC solutions were

On the additive artificial intelligence-based discovery of nanoparticle neurodegenerative disease drug delivery systems

• Shan He,
• Julen Segura Abarrategi,
• Harbil Bediaga,
• Sonia Arrasate and
• Humberto González-Díaz

Beilstein J. Nanotechnol. 2024, 15, 535–555, doi:10.3762/bjnano.15.47

• ) and n(cn4) = 16 coating agents (UC, PEG-Si(OMe)3, PVA, sodium citrate, 11-mercaptoundecanoic acid, PVP, propylamonium fragment, undecylazide fragment, CTAB, N,N,N-trimethyl-3(1-propene) ammonium fragment, potato starch, N-acetylcysteine, CMC-90, 2,3-dimercaptopropanesulfonate, 3

Luminescent gold nanoclusters for bioimaging applications

• Nonappa

Beilstein J. Nanotechnol. 2020, 11, 533–546, doi:10.3762/bjnano.11.42

• : glutathione; NAC: N-acetylcysteine; MTU: 5-methyl-2-thiouracil). D) Structures of biomolecular ligands (HSA: human serum albumin, PDB ID IE78; BSA: bovine serum albumin, PDB ID 3VO3, and Lys: lysozyme, PDB ID 3WUN). E) Schematic representation showing Au-BSA NC synthesis. F) Absorbance and fluorescence

Nanostructured surfaces by supramolecular self-assembly of linear oligosilsesquioxanes with biocompatible side groups

• Maria Nowacka,
• Anna Kowalewska and
• Tomasz Makowski

Beilstein J. Nanotechnol. 2015, 6, 2377–2387, doi:10.3762/bjnano.6.244

• surface roughness, thickness and the arrangement of macromolecules were noted depending on the kind of functional groups on the side chains. Specific changes in the morphology of the surface layer were observed when mica was primed with a monolayer of small organic compounds (e.g., N-acetylcysteine

• derivatives of N-acetylcysteine (NAC), cysteine hydrochloride (Cys-HCl) and glutathione (GSH). Such self-assembled PSAMs based on polysilsesquioxane materials are attractive for surface nanopatterning and bioengineering, including preparation of surfaces rich in organic groups typical of the extracellular

• used bare or primed, prior to the coating with LPSQ-COOH/X, with a monolayer of N-acetylcysteine, citric acid or thioglycolic acid. The primers are bound to mica by ionic bonds (carboxylates) and simultaneously provide the substrate with new organic functions capable of hydrogen bonding [49]. Atomic