Search results

Search for "SN38" in Full Text gives 4 result(s) in Beilstein Journal of Nanotechnology.

Vinorelbine-loaded multifunctional magnetic nanoparticles as anticancer drug delivery systems: synthesis, characterization, and in vitro release study

  • Zeynep Özcan and
  • Afife Binnaz Hazar Yoruç

Beilstein J. Nanotechnol. 2024, 15, 256–269, doi:10.3762/bjnano.15.24

Graphical Abstract
  • where the synthesized nanostructure was exposed to NIR light, SN38-loaded nanoparticles effectively suppressed tumor growth chemotherapeutically and photothermally [29]. This promising result highlights the potential of the PEGylation of PDA nanoparticles for advanced cancer treatment strategies
PDF
Album
Full Research Paper
Published 28 Feb 2024

Nanotechnology – a robust tool for fighting the challenges of drug resistance in non-small cell lung cancer

  • Filip Gorachinov,
  • Fatima Mraiche,
  • Diala Alhaj Moustafa,
  • Ola Hishari,
  • Yomna Ismail,
  • Jensa Joseph,
  • Maja Simonoska Crcarevska,
  • Marija Glavas Dodov,
  • Nikola Geskovski and
  • Katerina Goracinova

Beilstein J. Nanotechnol. 2023, 14, 240–261, doi:10.3762/bjnano.14.23

Graphical Abstract
PDF
Album
Review
Published 22 Feb 2023

Multilayer capsules made of weak polyelectrolytes: a review on the preparation, functionalization and applications in drug delivery

  • Varsha Sharma and
  • Anandhakumar Sundaramurthy

Beilstein J. Nanotechnol. 2020, 11, 508–532, doi:10.3762/bjnano.11.41

Graphical Abstract
PDF
Album
Review
Published 27 Mar 2020

Magnetic-Fe/Fe3O4-nanoparticle-bound SN38 as carboxylesterase-cleavable prodrug for the delivery to tumors within monocytes/macrophages

  • Hongwang Wang,
  • Tej B. Shrestha,
  • Matthew T. Basel,
  • Raj K. Dani,
  • Gwi-Moon Seo,
  • Sivasai Balivada,
  • Marla M. Pyle,
  • Heidy Prock,
  • Olga B. Koper,
  • Prem S. Thapa,
  • David Moore,
  • Ping Li,
  • Viktor Chikan,
  • Deryl L. Troyer and
  • Stefan H. Bossmann

Beilstein J. Nanotechnol. 2012, 3, 444–455, doi:10.3762/bjnano.3.51

Graphical Abstract
  • to the tumor site is highly desirable in cancer treatment, because it is capable of minimizing collateral damage. Herein, we report the synthesis of a nanoplatform, which is composed of a 15 ± 1 nm diameter core/shell Fe/Fe3O4 magnetic nanoparticles (MNPs) and the topoisomerase I blocker SN38 bound
  • /macrophage-like cells (Mo/Ma)), which have been engineered to express intracellular carboxylesterase (InCE) upon addition of doxycycline by a Tet-On Advanced system. The nanoplatform was taken up efficiently by these tumor-homing cells. They showed low toxicity even at high nanoplatform concentration. SN38
  • was released successfully by switching on the Tet-On Advanced system. We have demonstrated that this nanoplatform can be potentially used for thermochemotherapy. We will be able to achieve the following goals: (1) Specifically deliver the SN38 prodrug and magnetic nanoparticles to the cancer site as
PDF
Album
Supp Info
Full Research Paper
Published 13 Jun 2012
Other Beilstein-Institut Open Science Activities