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Search for "biological fluids" in Full Text gives 36 result(s) in Beilstein Journal of Nanotechnology.
Protein corona – from molecular adsorption to physiological complexity
Beilstein J. Nanotechnol. 2015, 6, 857–873, doi:10.3762/bjnano.6.88
- was suggested that charge distributions on the protein surface, rather than the overall molecular charge, govern the Coulomb interactions between NP and protein [9]. This intriguing idea seems indeed very relevant, considering that the Debye length at the typical ionic strengths of biological fluids
Biological responses to nanoscale particles
Beilstein J. Nanotechnol. 2015, 6, 380–382, doi:10.3762/bjnano.6.37
- conjugates of biomolecules, magnetism, radioactivity, Janus particles and core–shell particles were combined. In particular, the use of fluorescently labeled particles has become one of the preferred tools to track nanoparticles inside cells and tissue. When nanoparticles are exposed to biological fluids
Functionalized polystyrene nanoparticles as a platform for studying bio–nano interactions
Beilstein J. Nanotechnol. 2014, 5, 2403–2412, doi:10.3762/bjnano.5.250
- ]. Polystyrene is biocompatible and is not expected to adversely affect interactions of nanoparticles with biological systems. Specifically surface-modified polystyrene nanoparticles are homogeneous, exhibit a low polydispersity index, and form stable colloids in biological fluids [34]. We have used polystyrene
Effects of surface functionalization on the adsorption of human serum albumin onto nanoparticles – a fluorescence correlation spectroscopy study
Beilstein J. Nanotechnol. 2014, 5, 2036–2047, doi:10.3762/bjnano.5.212
- attention. Considering the wide variety of existing NPs and the complexity of biological fluids, substantial variations in their mutual interactions can be expected. Knowledge of these interactions is, however, indispensible for safe applications of NPs in the field of nanomedicine, for example, as highly
Influence of surface-modified maghemite nanoparticles on in vitro survival of human stem cells
Beilstein J. Nanotechnol. 2014, 5, 1732–1737, doi:10.3762/bjnano.5.183
- stealth particles with reduced opsonization in biological fluids. These properties can be exploited in magnetic resonance imaging and tracking of iron oxide-labeled cells, for the magnetic separation of cells, nucleic acids and proteins and in medicine for treatments by using targeted drug delivery
In vitro and in vivo interactions of selected nanoparticles with rodent serum proteins and their consequences in biokinetics
Beilstein J. Nanotechnol. 2014, 5, 1699–1711, doi:10.3762/bjnano.5.180
- of the NP is determined by the types of proteins covering the NP. In other words, the physicochemical properties of the NP play an essential role during protein binding but the biokinetics is largely determined by the covering proteins and their dynamic exchange in various biological fluids. This
Current state of laser synthesis of metal and alloy nanoparticles as ligand-free reference materials for nano-toxicological assays
Beilstein J. Nanotechnol. 2014, 5, 1523–1541, doi:10.3762/bjnano.5.165
- controlled independently while their uniquely high purity is retained. Hence, this article will highlight totally surfactant-free size control strategies for laser-fabricated nanoparticles and will comment on the stability of these particles in biological fluids. Additionally, laser-based synthesis methods
- particle concentrations. An electrostatically-controlled approach for ligand-free size control of gold nanoparticle is the in situ addition of simple inorganic electrolytes like NaCl or sodium phosphate buffer. These additives are frequently found in most biological fluids and hence are not prone to
- salinities, however, are not realistic for toxicological assays and are solely required during synthesis. Hence, upon exposition to biological fluids like blood, significantly higher ionic strengths (≈200 mM) may be found. This means that upon addition of the nanoparticles to biological fluids, 1/κ is
The protein corona protects against size- and dose-dependent toxicity of amorphous silica nanoparticles
Beilstein J. Nanotechnol. 2014, 5, 1380–1392, doi:10.3762/bjnano.5.151
- major factor (co)determining their biological identity and hence, effects at the nano–bio interface [22]. In biological fluids, proteins bind to the surface of nanoparticles to form a biological coating around the nanoparticle, known as the protein corona. Over the time, this corona evolves and may
Mimicking exposures to acute and lifetime concentrations of inhaled silver nanoparticles by two different in vitro approaches
Beilstein J. Nanotechnol. 2014, 5, 1357–1370, doi:10.3762/bjnano.5.149
- into the environment (such as for instance air or water, experimental media or biological fluids) are subject to a number of processes (such as aggregation and oxidation with the formation of Ag+) that alter their physico-chemical characteristics. These possible processes influence the mode of
Characterization of protein adsorption onto FePt nanoparticles using dual-focus fluorescence correlation spectroscopy
Beilstein J. Nanotechnol. 2011, 2, 374–383, doi:10.3762/bjnano.2.43
- due to their large surface-to-volume ratio [3] and, therefore, NPs may also pose a biological hazard [4][5]. Upon incorporation into the body, NPs become exposed to biological fluids such as lung epithelial lining fluid or blood plasma, which contain a variety of dissolved molecules, especially
Magnetic nanoparticles for biomedical NMR-based diagnostics
Beilstein J. Nanotechnol. 2010, 1, 142–154, doi:10.3762/bjnano.1.17
- these advantages, the sample volume for DMR detection could be reduced by a factor of ~10 (to 1 µL) compared to the previous devices (~10 µL). The microfluidic networks in the DMR system facilitate the handling of biological fluids, the effective mixing of MNPs with small sample volumes, and the
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