Beilstein J. Nanotechnol.2025,16, 1504–1521, doi:10.3762/bjnano.16.106
erroneous conclusions about the efficacy of conjugation reactions, which can have detrimental impacts on the functionality and safety of IONPs in biomedical applications.
Keywords: click chemistry; copper-catalyzed azide–alkyne cycloaddition; disulfidereduction; iron oxide nanoparticles; thiol–maleimide
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Figure 1:
Structural formulae of ligands, amine linkers, disulfide reducing agents, and clickable dyes used i...