Beilstein J. Nanotechnol.2010,1, 3–13, doi:10.3762/bjnano.1.2
conformation of a surface-grafted PEG layer, and how this might influence its interfacial properties may prove beneficial towards optimizing the PEGylation process. Although techniques such as X-ray photoelectron spectroscopy (XPS) [6][7] and ellipsometry [8] have been proven powerful in terms of studying
chains into their swelling state.
Discussion
We have studied the behavior of 20 kDa mPEG–SH “grafted to” Au surfaces using a microcantilever array-based sensor. Consistent with XPS [8], ellipsometry [8][34], QCM [35] and AFM [36] polymer “grafting to” studies, we find that the adsorption profile of mPEG
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Figure 1:
(A) Scanning electron microscope image of a silicon microcantilever array consisting of eight canti...