Advances of aptamers in esophageal cancer diagnosis, treatment and drug delivery

• Yang Fei,
• Hui Xu,
• Chunwei Zhang,
• Jingjing Wang and
• Yong Jin

Beilstein J. Nanotechnol. 2025, 16, 1734–1750, doi:10.3762/bjnano.16.121

• Yang Fei Hui Xu Chunwei Zhang Jingjing Wang Yong Jin School of Pharmaceutical Sciences, Anhui Medical University, Hefei, Anhui, China 10.3762/bjnano.16.121 Abstract Esophageal cancer (EC) is a common malignant tumor of the digestive tract with poor prognosis and high mortality. The early

• conjugates and aptamer-functionalized drug nanocarriers for targeted drug delivery in esophageal cancer are reviewed in this paper. In addition, we expect investigators to pay special attention to improving aptamer permeability and stability to accelerate aptamer clinical transformation. In conclusion

• , leveraging the high target specificity of well-selected aptamers may bring new breakthroughs in the diagnosis, treatment and drug delivery of EC. Keywords: aptamers; detection; drug delivery; esophageal cancer; esophageal squamous cell carcinoma; therapy; Review 1 Introduction Esophageal cancer (EC) is

Photothermal ablation of murine melanomas by Fe₃O₄ nanoparticle clusters

• Xue Wang,
• Lili Xuan and
• Ying Pan

Beilstein J. Nanotechnol. 2022, 13, 255–264, doi:10.3762/bjnano.13.20

• effects of alumina-coated Fe3O4 nanoparticles against bacteria upon exposure to NIR light [13]. Further studies with esophageal cancer demonstrate that Fe3O4 nanoparticles induce hyperthermia post absorption to suppress tumor growth in a dosage-dependent manner [14]. However, due to very high dosage

Use of nanosystems to improve the anticancer effects of curcumin

• Andrea M. Araya-Sibaja,
• Norma J. Salazar-López,
• Krissia Wilhelm Romero,
• José R. Vega-Baudrit,
• J. Abraham Domínguez-Avila,
• Carlos A. Velázquez Contreras,
• Ramón E. Robles-Zepeda,
• Mirtha Navarro-Hoyos and
• Gustavo A. González-Aguilar

Beilstein J. Nanotechnol. 2021, 12, 1047–1062, doi:10.3762/bjnano.12.78

• esophageal cancer) and to reduce drug resistance. However, further research is necessary to validate its possible beneficial effects in humans. It should also be emphasized that there is significant variation in the metabolism and rate of nanosystems in experimental animals as compared to humans. For example