Gold nanoparticles covalently assembled onto vesicle structures as possible biosensing platform

• M. Fátima Barroso,
• M. Alejandra Luna,
• Juan S. Flores Tabares,
• Cristina Delerue-Matos,
• N. Mariano Correa,
• Fernando Moyano and
• Patricia G. Molina

Beilstein J. Nanotechnol. 2016, 7, 655–663, doi:10.3762/bjnano.7.58

• ; Introduction Vesicles are spherical structures composed primarily of phospholipids and these are organized in bilayers. These vesicles contain an internal aqueous phase and are suspended in an external aqueous phase. Therefore, the vesicles may contain lipophilic substances, which are located in the

Pulmonary surfactant augments cytotoxicity of silica nanoparticles: Studies on an in vitro air–blood barrier model

• Jennifer Y. Kasper,
• Lisa Feiden,
• Maria I. Hermanns,
• Christoph Bantz,
• Michael Maskos,
• Ronald E. Unger and
• C. James Kirkpatrick

Beilstein J. Nanotechnol. 2015, 6, 517–528, doi:10.3762/bjnano.6.54

• ]. Thus, in vitro studies focusing on cytotoxicity of NPs at and transport of NPs across this cellular air–blood barrier, must take into account that a prior interaction of NPs with pulmonary surfactant components will occur. Pulmonary surfactant comprises up to 90% phospholipids (phosphatidylcholines

• surfactant substitution and originated from bovine alveolar lavage. It is composed of surfactant proteins SP-B and SP-C as well as phospholipids. It was suspended in PBS (phosphate-buffered saline) at a concentration of 40 mg/mL. Cell culture: ISO-HAS-1 (human microvascular endothelial cell line, originated

• its inter-head groups, which causes a higher mobility of the N(CH3)3+ group terminus of the phospholipids. Consequently, silica alters the membrane permeability and the fluidity of the bilayers is decreased, which finally leads to membrane perturbation and disruption [36]. The latter can be sensed by

Functionalization of α-synuclein fibrils

• Simona Povilonienė,
• Vida Časaitė,
• Virginijus Bukauskas,
• Arūnas Šetkus,
• Juozas Staniulis and
• Rolandas Meškys

Beilstein J. Nanotechnol. 2015, 6, 124–133, doi:10.3762/bjnano.6.12

• , and the concentration of fatty acids, phospholipids and metal ions, were shown to induce and/or modulate the α-Syn structure and oligomerization in vitro [17][18]. The formation of fibrils is enhanced under acidic conditions (pH 4–6) and the morphology of matured fibrils is influenced by the shape of

Synthesis of boron nitride nanotubes and their applications

• Saban Kalay,
• Zehra Yilmaz,
• Ozlem Sen,
• Melis Emanet,
• Emine Kazanc and
• Mustafa Çulha

Beilstein J. Nanotechnol. 2015, 6, 84–102, doi:10.3762/bjnano.6.9

• only be used in biological applications after noncovalent [7] or covalent [15][16] modifications to increase their water dispersibility. Thus, they have been modified with several surface modifiers such as PEGylated phospholipids [17], and molecules of biological origin including DNA [18], proteins [13

Nanobioarchitectures based on chlorophyll photopigment, artificial lipid bilayers and carbon nanotubes

• Marcela Elisabeta Barbinta-Patrascu,
• Stefan Marian Iordache,
• Ana Maria Iordache,
• Nicoleta Badea and
• Camelia Ungureanu

Beilstein J. Nanotechnol. 2014, 5, 2316–2325, doi:10.3762/bjnano.5.240

• pristine and f-CNTs do not induce toxicity in mice [14][15][16][17]. On the other hand, biocoating SWCNTs with biomolecules such as phospholipids conveys biocompatibility and less toxicity to carbon nanotubes. Moreover, SWCNTs are characterized by less accumulation in body as compared to multi-walled

• could open new perspectives for biomedical and biotechnological applications. The increased interest in use of phospholipids is due to the fact that they are basic structural components of biomembranes and artificial lipid membranes (liposomes). Liposomes are spherical, soft-matter vesicles composed of

Model systems for studying cell adhesion and biomimetic actin networks

• Dorothea Brüggemann,
• Johannes P. Frohnmayer and
• Joachim P. Spatz

Beilstein J. Nanotechnol. 2014, 5, 1193–1202, doi:10.3762/bjnano.5.131

• solubilized in octyl glucoside and added to different nitrogen dried phospholipids. Afterwards, the protein–lipid mixture was dialysed against a 1000 fold excess of the integrin buffer without octyl glucoside [34]. This procedure yielded proteoliposomes with functional integrin for the first time, as it was

Cyclodextrin-poly(ε-caprolactone) based nanoparticles able to complex phenolphthalein and adamantyl carboxylate

• Daniela Ailincai and
• Helmut Ritter

Beilstein J. Nanotechnol. 2014, 5, 651–657, doi:10.3762/bjnano.5.76

• nanovesicles based on natural macromolecular compounds, liposomes formed by autoassemble of phospholipids in aqueous medium [1], and nanovesicles formed by the autoassemble of synthetic amphiphilic copolymers, polymersomes [2]. There is a broad variety of conditions which have to be met, both for nanoparticles

The optimal shape of elastomer mushroom-like fibers for high and robust adhesion

• Burak Aksak,
• Korhan Sahin and
• Metin Sitti

Beilstein J. Nanotechnol. 2014, 5, 630–638, doi:10.3762/bjnano.5.74

• ][3]. A recent study by Hsu et al. [4] suggests that the presence of phospholipids on the tips of the fibers aid in adhesion. It has also been shown that humidity levels change the clinging ability of geckos significantly [5][6][7][8]. Regardless of the adhesion mechanism, the cumulative effect from