DNA–melamine hybrid molecules: from self-assembly to nanostructures

• Rina Kumari,
• Shib Shankar Banerjee,
• Anil K. Bhowmick and
• Prolay Das

Beilstein J. Nanotechnol. 2015, 6, 1432–1438, doi:10.3762/bjnano.6.148

• Technology Kharagpur, Kharagpur 721302, India 10.3762/bjnano.6.148 Abstract Single-stranded DNA–melamine hybrid molecular building blocks were synthesized using a phosphoramidation cross-coupling reaction with a zero linker approach. The self-assembly of the DNA–organic hybrid molecules was achieved by DNA

• –organic hybrid; melamine; nanostructures; phosphoramidation; self-assembly; Findings The importance of DNA in the field of nanotechnology stems from the fact that DNA is a macromolecule on the nanoscale with self-assembling properties [1][2]. The molecular recognition through base pairing in DNA makes it

• amine groups of melamine and the subsequent construction of two distinct types of nanoassemblies out of the DNA–organic hybrid molecules are demonstrated here for the first time (Scheme 1). The 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) and imidazole-mediated phosphoramidation cross-coupling