Ultrasonic irradiation in the synthesis of nanohydroxyapatite: a chemically friendly technique for improving hemocompatibility and antibiofilm applications

• Juan Mendoza Turmero,
• Cristina Parra Pantoja,
• Marcos Sabino Gutiérrez,
• Milagro Fernández-Delgado,
• Claudia Alvarado-Castillo,
• Damarys Soto Gil,
• María E. Gomes Gomes,
• Yony Gutiérrez Barrios and
• Daniel Suárez Arteaga

Beilstein J. Nanotechnol. 2026, 17, 991–1015, doi:10.3762/bjnano.17.68

• previously, supports the highly promising and non-disruptive preliminary profile of the synthesized nanostructures. When assessing the hemotoxicity of a biomaterial, platelet aggregation must also be studied. This process is crucial for preventing many circulation-related diseases and pathologies, such as

• platelets must be studied since they participate in the first events that lead to the formation of blood clots, which are associated with the development of strokes and heart attacks [90]. Therefore, to evaluate the effect of nHA synthesized in W/THF on platelets, in vitro platelet aggregation tests were

• aggregation (SLP), nor the integral measurement of the entire aggregation process (AUC). Small variations (<10%) were observed, but they were not significant with respect to the control conditions. The inability of synthesized nHA to alter the natural process of platelet aggregation is very favorable and

Bio-imaging with the helium-ion microscope: A review

• Matthias Schmidt,
• James M. Byrne and
• Ilari J. Maasilta

Beilstein J. Nanotechnol. 2021, 12, 1–23, doi:10.3762/bjnano.12.1

• that coating, as required for SEM, introduces artefacts such as a granular structure on the cell surfaces and a partial closing of pores, thus highlighting one of the benefits of HIM. Bazou et al. also studied tumour cell-induced platelet aggregation by fluorescence microscopy and HIM. In this study

Identification of physicochemical properties that modulate nanoparticle aggregation in blood

• Ludovica Soddu,
• Duong N. Trinh,
• Eimear Dunne,
• Dermot Kenny,
• Giorgia Bernardini,
• Ida Kokalari,
• Arianna Marucco,
• Marco P. Monopoli and
• Ivana Fenoglio

Beilstein J. Nanotechnol. 2020, 11, 550–567, doi:10.3762/bjnano.11.44

• purpose of investigating the role of surface curvature and chemistry on platelet aggregation, activation and adhesion. Substantial differences were found in the composition of the protein corona depending on the chemical nature of the nanoparticles, while the surface curvature was found to play a minor

• , the results presented herein suggest the existence of independent modes of action that are differently affected by the physicochemical properties of the materials, potentially leading to vessel occlusion and/or formation of thrombi in vivo. Keywords: aggregation; nanoparticles; platelet aggregation

• platelet deposition in post-capillary venules in the liver and heart, suggesting the role of this protein in nanoparticle-mediated platelet aggregation [14][15]. Silica nanoparticles (SNPs) of different sizes were found to activate glycoprotein IIb/IIIa and to induce the expression of P-selectin in

Model systems for studying cell adhesion and biomimetic actin networks

• Dorothea Brüggemann,
• Johannes P. Frohnmayer and
• Joachim P. Spatz

Beilstein J. Nanotechnol. 2014, 5, 1193–1202, doi:10.3762/bjnano.5.131

• platelet aggregation and has been well characterised. The liposomes, into which the integrins were incorporated, had diameters of 40 ± 8 nm and can be characterised as small liposomes. Integrin reconstitution was carried out by a detergent-dialysis method. During reconstitution the purified integrins were