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Search for "protein nanoparticles" in Full Text gives 5 result(s) in Beilstein Journal of Nanotechnology.
Venom-loaded cationic-functionalized poly(lactic acid) nanoparticles for serum production against Tityus serrulatus scorpion
Beilstein J. Nanotechnol. 2025, 16, 1633–1643, doi:10.3762/bjnano.16.115
- ” is the total protein amount added and “free proteins” is the non-entrapped protein in the supernatant after centrifugation. Sodium dodecyl sulfate in polyacrylamide gel electrophoresis The electrophoretic profile of T. serrulatus venom, free-protein nanoparticles, and different concentrations of
The steep road to nonviral nanomedicines: Frequent challenges and culprits in designing nanoparticles for gene therapy
Beilstein J. Nanotechnol. 2023, 14, 351–361, doi:10.3762/bjnano.14.30
- polymeric (e.g., core–shell micelles), oligomeric (e.g., lipid nanoparticles), or biomacromolecular (e.g., protein nanoparticles) components complicates matters only further by generating a higher-than-normal background through non-specific interactions with the assay media. In addition, a significant bias
Systematic studies into uniform synthetic protein nanoparticles
Beilstein J. Nanotechnol. 2022, 13, 274–283, doi:10.3762/bjnano.13.22
- , or monodispersity. Electrohydrodynamic (EHD) jetting is a probate method to formulate synthetic protein nanoparticles (SPNPs), but a systematic understanding of the influence of crucial processing parameters, such as protein composition, on nanoparticle morphologies is still missing. Here, we address
- as poorly defined physical properties and/or stability in the bloodstream [14]. Desolvation methods have been used to prepare various therapeutic protein nanoparticles [15][16][17]. The desolvation process requires the addition of desolvating agents, such as ethanol or acetone, to induce changes in
- protein structure (sometimes fully denaturing the protein) and to cause subsequent precipitation of protein aggregates [18]. Self-assembly strategies also provide access to a variety of structurally diverse [19] protein nanoparticles. With the advent of in silico design and subsequent production of de
Electrokinetic characterization of synthetic protein nanoparticles
Beilstein J. Nanotechnol. 2020, 11, 1556–1567, doi:10.3762/bjnano.11.138
- treatment of a wide variety of diseases. However, the slow progress in the field has resulted in relatively few therapies being translated into the clinic. Anisotropic synthetic protein nanoparticles (ASPNPs) show potential as a next-generation drug-delivery technology, due to their biocompatibility
- ; bicompartmental particles; dielectrophoresis; electrokinetics; electrophoresis; electro-osmosis; microfluidics; protein nanoparticles; Introduction Over the past 30 years, nanoparticles have been developed for a wide variety of scientific applications, ranging from medical imaging to drug delivery and enzyme
- , naturally involved in biological molecule targeting, and are “smart” materials that can respond to various environmental cues, such as pH value, temperature, or target binding [4]. Protein nanoparticles (PNPs) are useful for the loading of active therapeutic enzymes and show potential results to be used as
Nanoencapsulation of ultra-small superparamagnetic particles of iron oxide into human serum albumin nanoparticles
Beilstein J. Nanotechnol. 2014, 5, 2259–2266, doi:10.3762/bjnano.5.235
- ethanol at a rate of 1.5 mL/min under permanent stirring (550 rpm). Afterwards, a volume of aqueous glutaraldehyde solution 8% [v/v] corresponding to between 100% and 600% of stoichiometric crosslinking of the amino groups in 50 mg HSA was added to stabilize the resulting protein nanoparticles. Particles
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