Hematopoietic and mesenchymal stem cells: polymeric nanoparticle uptake and lineage differentiation

• Ivonne Brüstle,
• Thomas Simmet,
• Gerd Ulrich Nienhaus,
• Katharina Landfester and
• Volker Mailänder

Beilstein J. Nanotechnol. 2015, 6, 383–395, doi:10.3762/bjnano.6.38

• intracellular depot of a drug or a nucleic acid construct with slow release kinetics. Thus, the intended nanoparticles should be tested for toxicity and the nanomaterial as a carrier ideally should not influence cellular functions itself, that is, only the payload should exert such an effect. Once introduced

Release behaviour and toxicity evaluation of levodopa from carboxylated single-walled carbon nanotubes

• Julia M. Tan,
• Jhi Biau Foo,
• Sharida Fakurazi and
• Mohd Zobir Hussein

Beilstein J. Nanotechnol. 2015, 6, 243–253, doi:10.3762/bjnano.6.23

• exhibited favourable, slow, sustained-release characteristics as a drug carrier with a release period over more than 20 h. The results obtained from the drug release studies of LD at different pH values showed that the LD-loaded nanohybrid is pH activated. The release kinetics of LD from SWCNT–COOH were

• therapeutic effect [26] and may benefit the treatment of PD. Release kinetics of LD To further analyse the release kinetics of LD from the SWCNT–COOH nanocarrier, pseudo-first-order (Equation 1), pseudo-second-order (Equation 2) and a parabolic diffusion equation (Equation 3) were adopted [3][27][28] as

Liquid fuel cells

• Grigorii L. Soloveichik

Beilstein J. Nanotechnol. 2014, 5, 1399–1418, doi:10.3762/bjnano.5.153

• ]. Hydrogen can be reversibly stored in metallic hydrides, e.g., intermetallic phases AB5 and AB3 [16], or complex hydrides, e.g., metal borohydrides M(BH4)n [17]. However, good hydrogen release kinetics and reversibility are inversely correlated with the storage capacity. Dehydrogenation of metal hydrides

Nanodiamond-DGEA peptide conjugates for enhanced delivery of doxorubicin to prostate cancer

• Amanee D Salaam,
• Patrick Hwang,
• Roberus McIntosh,
• Hadiyah N Green,
• Ho-Wook Jun and
• Derrick Dean

Beilstein J. Nanotechnol. 2014, 5, 937–945, doi:10.3762/bjnano.5.107

• drug concentrations, DOX efficacy was enhanced. The quantitative analysis of DOX release kinetics and cellular internalization are limitations of this study and should be the subject of future studies. Conclusion In this study, a novel targeted drug delivery system consisting of NDs (drug delivery

Injection of ligand-free gold and silver nanoparticles into murine embryos does not impact pre-implantation development

• Ulrike Taylor,
• Wiebke Garrels,
• Annette Barchanski,
• Svea Peterson,
• Laszlo Sajti,
• Andrea Lucas-Hahn,
• Lisa Gamrad,
• Ulrich Baulain,
• Sabine Klein,
• Wilfried A. Kues,
• Stephan Barcikowski and
• Detlef Rath

Beilstein J. Nanotechnol. 2014, 5, 677–688, doi:10.3762/bjnano.5.80

• µg/mL] AgNP dispersion was added to a blastomere with a volume of 90 pL [56]. The chosen concentration of Ag+-ions was approximated based on previously reported ion release kinetics of silver colloids in aqueous solution [57]. Control co-incubations of embryos with equimolar KNO3 showed no effect

Near-infrared dye loaded polymeric nanoparticles for cancer imaging and therapy and cellular response after laser-induced heating

• Tingjun Lei,
• Alicia Fernandez-Fernandez,
• Romila Manchanda,
• Yen-Chih Huang and
• Anthony J. McGoron

Beilstein J. Nanotechnol. 2014, 5, 313–322, doi:10.3762/bjnano.5.35

• compared to the free form [24]. Our release kinetics and pharmacokinetics study results [24] seem to indicate that the NP formulation stabilizes IR820, protecting it from degradation and allowing for longer detection windows. Discussion The MW of PGMD polymer is 3000 Da, which is expected for polymers