Current state of laser synthesis of metal and alloy nanoparticles as ligand-free reference materials for nano-toxicological assays

• Christoph Rehbock,
• Jurij Jakobi,
• Lisa Gamrad,
• Selina van der Meer,
• Daniela Tiedemann,
• Ulrike Taylor,
• Wilfried Kues,
• Detlef Rath and
• Stephan Barcikowski

Beilstein J. Nanotechnol. 2014, 5, 1523–1541, doi:10.3762/bjnano.5.165

• [162], Ag and Au [163] nanoparticles in in vivo trials on rats. Details related to all the above mentioned studies are summarized in Table 2. Conclusion Risk assessment in medical implant approval requires the quantification of unintended effects related to wear debris on the nanoscale. Hence, suitable

Mimicking exposures to acute and lifetime concentrations of inhaled silver nanoparticles by two different in vitro approaches

• Fabian Herzog,
• Kateryna Loza,
• Sandor Balog,
• Martin J. D. Clift,
• Matthias Epple,
• Peter Gehr,
• Alke Petri-Fink and
• Barbara Rothen-Rutishauser

Beilstein J. Nanotechnol. 2014, 5, 1357–1370, doi:10.3762/bjnano.5.149

• , an expression of SOD1 and HMOX1 was not induced. Discussion There is an urgent need for realistic exposure scenarios for in vitro toxicity testing of nanomaterials. We considered in this study the three main important points for inhalation risk assessment studies: realistic NP application simulating