Beilstein J. Nanotechnol.2012,3, 324–328, doi:10.3762/bjnano.3.36
capability, the sapphire substrate was patterned by using a grid of gold pillars as shown in Figure 1a.
The center-to-center distance of the pillars is 5 μm and the pillar height 75 nm. Four pillars form a singlecell, which can be repeatedly addressed in both an optical microscope and by AFM by simply
PDF
Figure 1:
(a) An optical image of nine different reference grids on a 10 × 10 mm2 sapphire substrate; (b) Opt...
Beilstein J. Nanotechnol.2010,1, 142–154, doi:10.3762/bjnano.1.17
and the highly magnetic MnFe2O4 nanoparticles, detection sensitivity for cell sensing was remarkably improved (Figure 7a) [15]. Notably, as shown in Figure 7b, the detection threshold was reduced to approximately single-cell level, far surpassing the sensitivity seen in either previous DMR experiments
PDF
Figure 1:
DMR assay configurations with magnetic nanoparticles (MNPs). (a) Magnetic relaxation switching (MRS...