Beilstein J. Nanotechnol.2021,12, 808–862, doi:10.3762/bjnano.12.64
, and sonoporation. These effects can result in the release of encapsulated drugs or genes at the site of interest as well as cell death and considerable image enhancement. The present review discusses US-responsive theranostic nanomaterials under the following categories: MBs, micelles, liposomes
therapy; sonoporation; theranostics; ultrasound; ultrasound responsive nanomaterials; Review
Introduction
Smart drug delivery vehicles
It is well known that the administration of most anticancer drugs can produce considerable systemic toxicity, which in some cases can be dose-limiting. Whether oral
weight molecules, such as nucleic acids, proteins, peptides, calcein, dextran [66][67][68][69][70], or gene complexes [67] via a process known as “sonoporation” or “transient cavitation”. Cavitation events are sometimes triggered by the effects of US on MBs. Microbubbles are micrometer-sized (1–10 µm