Nanocarrier strategies to overcome P-glycoprotein-mediated drug resistance in cancer therapy

• Andreina Quevedo-Enríquez,
• Katty Yi Zhang,
• Denisse Yajaira Enriquez,
• Byron Raul Inapanta,
• Roxana Noemí Peroni and
• Christian Rafael Quijia

Beilstein J. Nanotechnol. 2026, 17, 882–921, doi:10.3762/bjnano.17.64

• . Keywords: cancer chemotherapy; efflux transporters; multidrug resistance (MDR); nanoparticles; siRNA nanocarriers; tumor-targeted therapy; Review 1 Introduction 1.1 Cancer and current challenges in chemotherapy Cancer remains one of the leading causes of mortality worldwide, with millions of new cases