Realizing active targeting in cancer nanomedicine with ultrasmall nanoparticles

• André F. Lima,
• Giselle Z. Justo and
• Alioscka A. Sousa

Beilstein J. Nanotechnol. 2024, 15, 1208–1226, doi:10.3762/bjnano.15.98

• function as a more conventional NP platform in nanomedicine applications [18][21][22][38][39][40]. In diagnostic applications, usNPs have been employed in diverse imaging modalities, including optical imaging [41][42], X-ray computer tomography [43], photoacoustic imaging [41][44], magnetic resonance

Synthesis, characterization and anticancer effect of doxorubicin-loaded dual stimuli-responsive smart nanopolymers

• Ömür Acet,
• Pavel Kirsanov,
• Burcu Önal Acet,
• Inessa Halets-Bui,
• Dzmitry Shcharbin,
• Şeyda Ceylan Cömert and
• Mehmet Odabaşı

Beilstein J. Nanotechnol. 2024, 15, 1189–1196, doi:10.3762/bjnano.15.96

• inhibited at pH 5.0 in a medium with DOX–polyelectrolyte multilayers [41]. Regarding the possibility of using DOX-SNP complexes in vivo we can refer to the behavior of the similar PEG-PLGA-DOX polymersome complex [42]. It was found that PEG-PLGA-DOX polymersomes accumulated in tumor lesions, and after 48 h

• heamatological tests. The authors concluded that DOX polymersomes have less side effects than Doxil because of the biodegradability and release features of the complex [42]. Conclusion Specifically designed nanomedicines can deliver various agents simultaneously to a desired site of action, resulting in more

AI-assisted models to predict chemotherapy drugs modified with C₆₀ fullerene derivatives

• Jonathan-Siu-Loong Robles-Hernández,
• Dora Iliana Medina,
• Katerin Aguirre-Hurtado,
• Marlene Bosquez,
• Roberto Salcedo and
• Alan Miralrio

Beilstein J. Nanotechnol. 2024, 15, 1170–1188, doi:10.3762/bjnano.15.95

• obtaining an additional electron. Methods First, 42 drugs related to chemotherapy treatments for breast cancer were proposed. Although the most notable fullerene derivatives for biological applications are those with several hydrophilic groups, the carboxylic acid derivative C60–COOH has been studied as

• ) is obtained as the reference density ρ0 perturbed by density fluctuations δρ, that is, For all calculations within DFTB3, the 3OB parameter set was used [41]. To carry out the global optimization procedure, Balloon 1.8.2 [42] and DFTB+ 17.1 [40] were used for the initial conformational study by

Quantum-to-classical modeling of monolayer Ge₂Se₂ and its application in photovoltaic devices

• Anup Shrivastava,
• Shivani Saini,
• Dolly Kumari,
• Sanjai Singh and
• Jost Adam

Beilstein J. Nanotechnol. 2024, 15, 1153–1169, doi:10.3762/bjnano.15.94

• , respectively. All optimized structural parameters excellently match with previously reported values [41][42]. In addition to the lattice parameters for the monolayer Ge2Se2, we have optimized the vacuum slab in a normal direction to avoid interlayer interactions. The optimized vacuum level was found to be 23 Å

• [41][42][46][47]. The optimum bandgap value and its CBM/VBM positions make it suitable for photovoltaic applications and provide a guideline for selecting the absorber layers in the solar cells. Notably, multivalley and flat bands are present in the energy band structure. The formation of multiple

Photocatalytic methane oxidation over a TiO₂/SiNWs p–n junction catalyst at room temperature

• Qui Thanh Hoai Ta,
• Luan Minh Nguyen,
• Ngoc Hoi Nguyen,
• Phan Khanh Thinh Nguyen and
• Dai Hai Nguyen

Beilstein J. Nanotechnol. 2024, 15, 1132–1141, doi:10.3762/bjnano.15.92

• phase (JCPDS No.27-1402) [40][41]. In the case of the as-synthesized composite, the favored growth of TiO2(101) on the surface of p-Si NWs has been noticed [42]. The minor (112), (200), (105), and (211) peaks at 2θ = 38.2°, 48.5°, 53.3°, and 55.1° indicate the formation of anatase TiO2 (JCPDS No.21-1272

Local work function on graphene nanoribbons

• Daniel Rothhardt,
• Amina Kimouche,
• Tillmann Klamroth and
• Regina Hoffmann-Vogel

Beilstein J. Nanotechnol. 2024, 15, 1125–1131, doi:10.3762/bjnano.15.91

• for 1.18 nm. These features are consistent with previous results revealing a distance dependence of the LCPD or the electrostatic forces [41][42][43][44]. In general, we expect an exponential decay of the electrostatic field 2D Fourier components, where the decay constant λ is the lateral wavelength

Recent updates in applications of nanomedicine for the treatment of hepatic fibrosis

• Damai Ria Setyawati,
• Fransiska Christydira Sekaringtyas,
• Riyona Desvy Pratiwi,
• A’liyatur Rosyidah,
• Rohimmahtunnissa Azhar,
• Nunik Gustini,
• Gita Syahputra,
• Idah Rosidah,
• Etik Mardliyati,
• Tarwadi and
• Sjaikhurrizal El Muttaqien

Beilstein J. Nanotechnol. 2024, 15, 1105–1116, doi:10.3762/bjnano.15.89

• permeability are increased because of angiogenesis within the tumor microenvironment [41]. The fenestrae of the liver endothelial cells increase to approximately 400–600 nm, often accompanied with impaired lymphatic drainage, leading to the EPR effect [42]. In contrast, the excessive production of ECM by the

Unveiling the potential of alginate-based nanomaterials in sensing technology and smart delivery applications

• Shakhzodjon Uzokboev,
• Khojimukhammad Akhmadbekov,
• Ra’no Nuritdinova,
• Salah M. Tawfik and
• Yong-Ill Lee

Beilstein J. Nanotechnol. 2024, 15, 1077–1104, doi:10.3762/bjnano.15.88

• potential risks or complications [42]. Recently, researchers and medical organizations have begun using low-cost biosensors to monitor food and water toxins, human biological processes, accurate health diagnostics, and for other applications [43]. Biosensor-based technologies are essential to assess samples

Effect of wavelength and liquid on formation of Ag, Au, Ag/Au nanoparticles via picosecond laser ablation and SERS-based detection of DMMP

• Sree Satya Bharati Moram,
• Chandu Byram and
• Venugopal Rao Soma

Beilstein J. Nanotechnol. 2024, 15, 1054–1069, doi:10.3762/bjnano.15.86

• ], pesticides on vegetables, dals [42], fruit surfaces [43], and explosives on rough surfaces [44][45]. In the last few years, our group has been continuously working on developing a flexible SERS substrate for the detection of various types of hazardous molecules: aggregated Ag and Au NPs on filter paper [46

• discussions and comments. Funding SSBM acknowledges the SERB, India, for the NPDF funding (PDF/2023/000958/PMS). VRS acknowledges IoE-UoH through a project funded by the Institute of Eminence (#UOH/IOE/RC1/RC1-20-016). VRS also acknowledges the financial support from DRDO, India [#ERIP/ER/1501138/M/01/319/D(R

Interface properties of nanostructured carbon-coated biological implants: an overview

• Mattia Bartoli,
• Francesca Cardano,
• Erik Piatti,
• Stefania Lettieri,
• Andrea Fin and
• Alberto Tagliaferro

Beilstein J. Nanotechnol. 2024, 15, 1041–1053, doi:10.3762/bjnano.15.85

• another (inter-layer transport) and is the source of the large anisotropy typically displayed between in-plane and out-of-plane carrier mobilities [42]. Carrier injection is usually determined by energy band alignment and interface transparency, and it is limited by the number of available conduction

Atomistic insights into the morphological dynamics of gold and platinum nanoparticles: MD simulations in vacuum and aqueous media

• Evangelos Voyiatzis,
• Eugenia Valsami-Jones and
• Antreas Afantitis

Beilstein J. Nanotechnol. 2024, 15, 995–1009, doi:10.3762/bjnano.15.81

• carried out by Wen et al. [41]. Wang et al. employed ab initio MD to describe the melting of icosahedral Au nanoclusters [42]. The structural and thermal stability of high-index-faceted Pt NPs was addressed by Zeng et al. [43]. Similarly, the thermal stability of unsupported Au NPs was investigated by

Recent progress on field-effect transistor-based biosensors: device perspective

• Billel Smaani,
• Fares Nafa,
• Mohamed Salah Benlatrech,
• Ismahan Mahdi,
• Hamza Akroum,
• Mohamed walid Azizi,
• Khaled Harrar and
• Sayan Kanungo

Beilstein J. Nanotechnol. 2024, 15, 977–994, doi:10.3762/bjnano.15.80

• technology rapidly emerged [40][41]. However, all these FETs were highly bulky and required more space. Nakamoto et al. [42] later devised a biosensor with a novel fabrication method aligned well with the complementary metal–oxide–semiconductor (CMOS) fabrication process. Usually, biosensors convert

Beyond biomimicry – next generation applications of bioinspired adhesives from microfluidics to composites

• Dan Sameoto

Beilstein J. Nanotechnol. 2024, 15, 965–976, doi:10.3762/bjnano.15.79

• 2010 with the advent of the modern soft robotics field. Traditional stiffness-switching mechanisms include phase change materials [39], jamming actuators [40], electrorheological fluids [41], and antagonistic actuators [42], but vacuum jamming has been the most popular in academic literature [43

Therapeutic effect of F127-folate@PLGA/CHL/IR780 nanoparticles on folate receptor-expressing cancer cells

• Thi Ngoc Han Pham,
• Phuong-Thao Dang-Luong,
• Hong-Phuc Nguyen,
• Loc Le-Tuan,
• Xuan Thang Cao,
• Thanh-Danh Nguyen,
• Vy Tran Anh and
• Hieu Vu_Quang

Beilstein J. Nanotechnol. 2024, 15, 954–964, doi:10.3762/bjnano.15.78

• cancer treatment. The bigger the nanoparticles, the faster they would be cleared by the mononuclear phagocyte system [41], while those smaller than 6 nm would be excreted into the Bowman space of the kidney [42]. In addition to size, nanoparticle charge is also crucial for boosting its circulation in the

• than the negative ones [42]. Preventing protein absorption by nanoparticles might enhance the systemic half-life of nanoparticles. According to reports, nanoparticles with a stealth surface have a longer half-life [39]. Typically, hydrophilic substances, such as PVA and PEG, serve as stealth surface

Electrospun nanofibers: building blocks for the repair of bone tissue

• Tuğrul Mert Serim,
• Gülin Amasya,
• Tuğba Eren-Böncü,
• Ceyda Tuba Şengel-Türk and
• Ayşe Nurten Özdemir

Beilstein J. Nanotechnol. 2024, 15, 941–953, doi:10.3762/bjnano.15.77

• ]. The simplicity and cost-effectiveness of the electrospinning technique, its ability to use a wide variety of synthetic, natural, and mixed polymers, and the formation of highly porous and continuous fibers are the remarkable features of this method [42]. Although the use of electrospinning has become

Effects of cutting tool geometry on material removal of a gradient nanograined CoCrNi medium entropy alloy

• Yu-Sheng Lu,
• Yu-Xuan Hung,
• Thi-Xuyen Bui and
• Te-Hua Fang

Beilstein J. Nanotechnol. 2024, 15, 925–940, doi:10.3762/bjnano.15.76

• has been the subject of theoretical analyses, such as MD simulations [41], to predict the outcomes of ultraprecision machining [42]. This section investigates the effect of three RTS values of 0.5, 1.0, and 2.0 under various cutting depths (a = 0.5, 1.0, and 2.0 nm) and cutting-edge radii (r = 0.5

Identification of structural features of surface modifiers in engineered nanostructured metal oxides regarding cell uptake through ML-based classification

• Indrasis Dasgupta,
• Totan Das,
• Biplab Das and
• Shovanlal Gayen

Beilstein J. Nanotechnol. 2024, 15, 909–924, doi:10.3762/bjnano.15.75

• using the fivefold cross-validation procedure. Additionally, the model’s quality was evaluated by looking at the receiver operating characteristic (ROC) plot as well as specificity, sensitivity, and accuracy values [40][41][42]. Development of other machine learning models Calculation of descriptors and

The effect of age on the attachment ability of stick insects (Phasmatodea)

• Marie Grote,
• Stanislav N. Gorb and
• Thies H. Büscher

Beilstein J. Nanotechnol. 2024, 15, 867–883, doi:10.3762/bjnano.15.72

• stiffness of the cuticle of these organs and the internal pressure are important for the functionality and likely susceptible to decay during ageing [42][43]. We investigated the change in attachment ability and tarsal morphology in the species Sungaya aeta Hennemann, 2023 (Heteropterygidae). Members of

A review on the structural characterization of nanomaterials for nano-QSAR models

• Salvador Moncho,
• Eva Serrano-Candelas,
• Jesús Vicente de Julián-Ortiz and
• Rafael Gozalbes

Beilstein J. Nanotechnol. 2024, 15, 854–866, doi:10.3762/bjnano.15.71

• substituents differ (e.g., different organic ligands). The substituents can be organic chemicals as, for example, in the model developed from the database by Weissleder et al. [42] for several same-core superparamagnetic nanoparticles functionalized with different organic molecules. The authors used SMILES

Intermixing of MoS₂ and WS₂ photocatalysts toward methylene blue photodegradation

• Maryam Al Qaydi,
• Nitul S. Rajput,
• Michael Lejeune,
• Abdellatif Bouchalkha,
• Mimoun El Marssi,
• Steevy Cordette,
• Chaouki Kasmi and
• Mustapha Jouiad

Beilstein J. Nanotechnol. 2024, 15, 817–829, doi:10.3762/bjnano.15.68

• pollutants is often driven by reactive agents, such as superoxide radicals, hydroxyl radicals, or photo-induced holes produced from either the conduction or valence bands [41][42]. The mechanism of the PD of MB under visible light excitation consists of several steps: Initially, the MB dye molecules are

• valence band of MoS2 to WS2, potentially being captured by water molecules to form hydroxyl radicals. These hydroxyl radicals, in conjunction with valence band holes, contribute to the degradation of MB molecules into CO2 and H2O, as reported in different studies [42][43][44]. The effective separation of

Electrospun polysuccinimide scaffolds containing different salts as potential wound dressing material

• Veronika Pálos,
• Krisztina S. Nagy,
• Rita Pázmány,
• Krisztina Juriga-Tóth,
• Bálint Budavári,
• Judit Domokos,
• Dóra Szabó,
• Ákos Zsembery and
• Angela Jedlovszky-Hajdu

Beilstein J. Nanotechnol. 2024, 15, 781–796, doi:10.3762/bjnano.15.65

• ], biocompatible, and biodegradable polymer. Based on the literature, it is extensively researched for biomedical applications [21][33][34][35][36][37][38][39][40][41][42][43]. It is also known that PSI turns into polyaspartic acid (PASP) at physiological conditions, which is a degradable biomaterial [24][25][36

Exploring surface charge dynamics: implications for AFM height measurements in 2D materials

• Mario Navarro-Rodriguez,
• Andres M. Somoza and
• Elisa Palacios-Lidon

Beilstein J. Nanotechnol. 2024, 15, 767–780, doi:10.3762/bjnano.15.64

• sample [38][39][40][41], or to typically electrostatic conservative forces [42]. In the latter case, using KPFM to minimize these forces mitigates the problem. Finally, if the driving excitation frequency is tracked to follow the resonance frequency shift induced by the tip–sample interactions, the

Green synthesis of biomass-derived carbon quantum dots for photocatalytic degradation of methylene blue

• Dalia Chávez-García,
• Mario Guzman,
• Viridiana Sanchez and
• Rubén D. Cadena-Nava

Beilstein J. Nanotechnol. 2024, 15, 755–766, doi:10.3762/bjnano.15.63

• ; photoluminiscence; Introduction The textile industry is known for its high consumption of water, energy, and chemical reagents. For example, manufacturing a pair of indigo-dyed pants requires at least 42 L of water, plus approximately 21 L each time they are washed at home. To ensure product quality, textile dyes

• what has been previously reported [18][42]. In both cases, such modification in the D and G bands was correlated with the presence of heteroatoms in the CQD structure. The synthesis method reported in this work involves chemical (nitric acid treatment) and physical conditions (hydrothermal treatment

Effect of repeating hydrothermal growth processes and rapid thermal annealing on CuO thin film properties

• Monika Ozga,
• Eunika Zielony,
• Aleksandra Wierzbicka,
• Anna Wolska,
• Marcin Klepka,
• Marek Godlewski,
• Bogdan J. Kowalski and
• Bartłomiej S. Witkowski

Beilstein J. Nanotechnol. 2024, 15, 743–754, doi:10.3762/bjnano.15.62

• thin films can also be grown from liquid phases, employing techniques such as chemical bath deposition [31][32][33], successive ionic layer adsorption and reaction (SILAR) [34][35][36], sol–gel processes (using dip and spin coating) [37][38][39], as well as spray pyrolysis [40][41][42]. This work

Level set simulation of focused ion beam sputtering of a multilayer substrate

• Alexander V. Rumyantsev,
• Nikolai I. Borgardt,
• Roman L. Volkov and
• Yuri A. Chaplygin

Beilstein J. Nanotechnol. 2024, 15, 733–742, doi:10.3762/bjnano.15.61

• calculated ion trajectories for each angle θ was equal to 107. The electronic energy loss was described by the equipartition of Oen–Robinson [42] and Lindhard–Scharff [43] models. The atomic density of amorphous SiO2 was assumed as = 6.9·1022 cm−3 in accordance with [44]. Conclusion In this study, an