Advanced nanomedicine for drug delivery and biotherapy

Nanomedicine aims to design nanocarriers to deliver drugs into targeted tissues and cells. These drug delivery systems are applied to many fields of therapy and/or diagnosis. Their design, preparation and evaluation are related to the development of new methodologies and experimental models.

Biomolecules such as peptides, proteins and nucleic acids need specific attention for their development. They could benefit from being associated to nanocarriers to protect and deliver them to their site of action. They can also be utilized to functionalize the nanocarriers for active targeting and enhanced internalization.

The concept of “green nanomedicine” has recently emerged with the aims to reduce toxicity for patients and protect the environment. It concerns the active ingredients that can be natural molecules (from plants, bacteria) or obtained by green synthesis. Other research axes aim to develop environmentally friendly and cost-effective process (e.g., with solvent alternatives, energy optimization) to produce nanomedicines.

Contributions to this thematic issue are invited including, but not limited to, the following topics:

• Nanomedicines formulation and biological evaluation for therapy and/or diagnostics
• Organic chemistry, physical chemistry and analytical chemistry tools for nanomedicines
• Methodologies and experimental models, including the AI approach, in nanomedicine
• Eco-friendly conception, design and characterization of nanomedicines
• Administration, targeting and biodistribution of nanomedicines
• Regulatory approach for nanomedicines

 Submission deadline: July 30, 2026