Chiral phosphines in nucleophilic organocatalysis

Yumei Xiao, Zhanhu Sun, Hongchao Guo and Ohyun Kwon
Beilstein J. Org. Chem. 2014, 10, 2089–2121. https://doi.org/10.3762/bjoc.10.218

Cite the Following Article

Chiral phosphines in nucleophilic organocatalysis
Yumei Xiao, Zhanhu Sun, Hongchao Guo and Ohyun Kwon
Beilstein J. Org. Chem. 2014, 10, 2089–2121. https://doi.org/10.3762/bjoc.10.218

How to Cite

Xiao, Y.; Sun, Z.; Guo, H.; Kwon, O. Beilstein J. Org. Chem. 2014, 10, 2089–2121. doi:10.3762/bjoc.10.218

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  • Alves, A. J. S.; Silvestre, J. A. D.; Pinho e Melo, T. M. V. D. Continuous Flow Spirocyclization Reactions: Towards Efficient Synthesis of Chiral Spiropenicillanates. European Journal of Organic Chemistry 2024, 27. doi:10.1002/ejoc.202400689

Patents

  • KANG JUN YONG; MULLA KARIMULLA; ALESHIRE KYLE; FORSTER PAUL M. N-heterocyclic phosphines. US 10633403 B2, April 28, 2020.
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