(2R,1'S,2'R)- and (2S,1'S,2'R)-3-[2-Mono(di,tri)fluoromethylcyclopropyl]alanines and their incorporation into hormaomycin analogues

Scholarly Works

• Li, L.; Sivaguru, P.; Wei, D.; Liu, M.; Zhu, Q.; Dong, S.; Casali, E.; Li, N.; Zanoni, G.; Bi, X. Silver-catalyzed direct conversion of epoxides into cyclopropanes using N-triftosylhydrazones. Nature communications 2024, 15, 1951. doi:10.1038/s41467-024-46188-w
• Wang, C.; Zhu, D.; Wu, R.; Zhu, S. Dirhodium-Catalyzed Enantioselective Synthesis of Difluoromethylated Cyclopropanes via Enyne Cycloisomerization. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023, 11, e2306404. doi:10.1002/advs.202306404
• Zhang, X.; Tian, C.; Wang, Z.; Sivaguru, P.; Nolan, S. P.; Bi, X. Fluoroalkyl N-Triftosylhydrazones as Easily Decomposable Diazo Surrogates for Asymmetric [2 + 1] Cycloaddition: Synthesis of Chiral Fluoroalkyl Cyclopropenes and Cyclopropanes. ACS Catalysis 2021, 11, 8527–8537. doi:10.1021/acscatal.1c01483
• Chernykh, A. V.; Olifir, O. S.; Kuchkovska, Y. O.; Volochnyuk, D. M.; Yarmolchuk, V. S.; Grygorenko, O. O. Fluoroalkyl-Substituted Cyclopropane Derivatives: Synthesis and Physicochemical Properties. The Journal of organic chemistry 2020, 85, 12692–12702. doi:10.1021/acs.joc.0c01848
• Moschner, J.; Stulberg, V.; Fernandes, R.; Huhmann, S.; Leppkes, J.; Koksch, B. Approaches to Obtaining Fluorinated α-Amino Acids. Chemical reviews 2019, 119, 10718–10801. doi:10.1021/acs.chemrev.9b00024
• Levitskiy, O. A.; Grishin, Y. K.; Magdesieva, T. V. Stereoselective Electrosynthesis of β-Hydroxy-α-Amino Acids in the Form of NiII-Schiff-Base Complexes. European Journal of Organic Chemistry 2019, 2019, 3174–3182. doi:10.1002/ejoc.201900466
• Schlinquer, C.; Huang, W.-S.; Chen, L.; Poisson, T.; Pannecoucke, X.; Charette, A. B.; Jubault, P. Rhodium catalysed enantioselective synthesis of mono-(halo)-methyl-cyclopropanes. Organic & biomolecular chemistry 2019, 17, 472–476. doi:10.1039/c8ob03041c
• Tokairin, Y.; Soloshonok, V. A.; Moriwaki, H.; Konno, H. Asymmetric synthesis of (2S,3S)-3-Me-glutamine and (R)-allo-threonine derivatives proper for solid-phase peptide coupling. Amino acids 2018, 51, 419–432. doi:10.1007/s00726-018-2677-5
• Huang, W.-S.; Schlinquer, C.; Poisson, T.; Pannecoucke, X.; Charette, A. B.; Jubault, P. General Catalytic Enantioselective Access to Monohalomethyl and Trifluoromethyl Cyclopropanes. Chemistry (Weinheim an der Bergstrasse, Germany) 2018, 24, 10339–10343. doi:10.1002/chem.201802685
• Kotozaki, M.; Chanthamath, S.; Fujii, T.; Shibatomi, K.; Iwasa, S. Highly enantioselective synthesis of trifluoromethyl cyclopropanes by using Ru(ii)-Pheox catalysts. Chemical communications (Cambridge, England) 2018, 54, 5110–5113. doi:10.1039/c8cc02286k
• Bos, M.; Huang, W.; Poisson, T.; Pannecoucke, X.; Charette, A. B.; Jubault, P. Catalytic Enantioselective Synthesis of Highly Functionalized Difluoromethylated Cyclopropanes. Angewandte Chemie 2017, 129, 13504–13508. doi:10.1002/ange.201707375
• Bos, M.; Huang, W.-S.; Poisson, T.; Pannecoucke, X.; Charette, A. B.; Jubault, P. Catalytic Enantioselective Synthesis of Highly Functionalized Difluoromethylated Cyclopropanes. Angewandte Chemie (International ed. in English) 2017, 56, 13319–13323. doi:10.1002/anie.201707375
• Wang, Y.; Song, X.; Wang, J.; Moriwaki, H.; Soloshonok, V. A.; Liu, H. Recent approaches for asymmetric synthesis of α-amino acids via homologation of Ni(II) complexes. Amino acids 2017, 49, 1487–1520. doi:10.1007/s00726-017-2458-6
• Duan, Y.; Lin, J.-H.; Xiao, J.-C.; Gu, Y.-C. Difluoromethylcarbene for iron-catalyzed cyclopropanation. Chemical communications (Cambridge, England) 2017, 53, 3870–3873. doi:10.1039/c7cc01636k
• Hock, K. J.; Mertens, L.; Koenigs, R. M. Rhodium catalyzed synthesis of difluoromethyl cyclopropanes. Chemical communications (Cambridge, England) 2016, 52, 13783–13786. doi:10.1039/c6cc07745e

Explore citations to this article at