Cite the Following Article
Strategies in megasynthase engineering – fatty acid synthases (FAS) as model proteins
Manuel Fischer and Martin Grininger
Beilstein J. Org. Chem. 2017, 13, 1204–1211.
https://doi.org/10.3762/bjoc.13.119
How to Cite
Fischer, M.; Grininger, M. Beilstein J. Org. Chem. 2017, 13, 1204–1211. doi:10.3762/bjoc.13.119
Download Citation
Citation data can be downloaded as file using the "Download" button or used for copy/paste from the text window
below.
Citation data in RIS format can be imported by all major citation management software, including EndNote,
ProCite, RefWorks, and Zotero.
Presentation Graphic
| Picture with graphical abstract, title and authors for social media postings and presentations. | ||
| Format: PNG | Size: 594.6 KB | Download |
Citations to This Article
Up to 20 of the most recent references are displayed here.
Scholarly Works
- Schultz, K.; Costa-Pinheiro, P.; Gardner, L.; Pinheiro, L. V.; Ramirez-Solis, J.; Gardner, S. M.; Wellen, K. E.; Marmorstein, R. Snapshots of acyl carrier protein shuttling in human fatty acid synthase. Nature 2025, 641, 520–528. doi:10.1038/s41586-025-08587-x
- Paiva, P.; Medina, F. E.; Viegas, M. F.; Ferreira, P.; Neves, R. P. P.; Sousa, J. P. M.; Ramos, M. J.; Fernandes, P. A. Animal Fatty Acid Synthase: A Chemical Nanofactory. Chemical reviews 2021, 121, 9502–9553. doi:10.1021/acs.chemrev.1c00147
- Mindrebo, J. T.; Chen, A.; Kim, W. E.; Re, R. N.; Davis, T. D.; Noel, J. P.; Burkart, M. D. Structure and mechanistic analyses of the gating mechanism of elongating ketosynthases. ACS catalysis 2021, 11, 6787–6799. doi:10.1021/acscatal.1c00745
- Mindrebo, J. T.; Chen, A.; Kim, W. E.; Re, R. N.; Davis, T. D.; Noel, J. P.; Burkart, M. D. Structure and Mechanistic Analyses of the Gating Mechanism of Elongating Ketosynthases. 2021, 11, 6787–6799. doi:10.1101/2021.02.13.431092
- Stegemann, F.; Grininger, M. Comparative Study on Acyl Transferases in Fatty Acid and Polyketide Synthases. Cold Spring Harbor Laboratory 2020. doi:10.1101/2020.12.29.424742
- Mindrebo, J. T.; Patel, A.; Kim, W. E.; Davis, T. D.; Chen, A.; Bartholow, T. G.; La Clair, J. J.; McCammon, J. A.; Noel, J. P.; Burkart, M. D. Gating mechanism of elongating β-ketoacyl-ACP synthases. Nature communications 2020, 11, 1727. doi:10.1038/s41467-020-15455-x
- Fischer, M.; Joppe, M.; Mulinacci, B.; Vollrath, R.; Konstantinidis, K.; Kötter, P.; Ciccarelli, L.; Vonck, J.; Oesterhelt, D.; Grininger, M. Analysis of the co-translational assembly of the fungal fatty acid synthase (FAS). Scientific reports 2020, 10, 895. doi:10.1038/s41598-020-57418-8
- Mindrebo, J. T.; Patel, A.; Misson, L.; Kim, W. E.; Davis, T. D.; Ni, Q. Z.; La Clair, J. J.; Burkart, M. D. Structural Basis of Acyl-Carrier Protein Interactions in Fatty Acid and Polyketide Biosynthesis. Comprehensive Natural Products III; Elsevier, 2020; pp 61–122. doi:10.1016/b978-0-12-409547-2.14662-1
- Fernández-Cabezón, L.; Nikel, P. I. Advanced metabolic engineering strategies for the development of sustainable microbial processes. New and Future Developments in Microbial Biotechnology and Bioengineering; Elsevier, 2020; pp 225–246. doi:10.1016/b978-0-444-64301-8.00011-1
- Heil, C. S.; Wehrheim, S. S.; Paithankar, K. S.; Grininger, M. Fatty Acid Biosynthesis: Chain-Length Regulation and Control. Chembiochem : a European journal of chemical biology 2019, 20, 2298–2321. doi:10.1002/cbic.201800809
- Davis, T. D.; Michaud, J. M.; Burkart, M. D. Active site labeling of fatty acid and polyketide acyl-carrier protein transacylases. Organic & biomolecular chemistry 2019, 17, 4720–4724. doi:10.1039/c8ob03229g
- Fischer, M.; Mulinacci, B.; Joppe, M.; Vollrath, R.; Konstantinidis, K.; Kötter, P.; Ciccarelli, L.; Vonck, J.; Oesterhelt, D.; Grininger, M. Molecular mechanisms in fungal fatty acid synthase (FAS) assembly. Cold Spring Harbor Laboratory 2018, 336578. doi:10.1101/336578
