Synthesis of a dihalogenated pyridinyl silicon rhodamine for mitochondrial imaging by a halogen dance rearrangement

Jessica Matthias, Thines Kanagasundaram, Klaus Kopka and Carsten S. Kramer

Beilstein J. Org. Chem. 2019, 15, 2333–2343. doi:10.3762/bjoc.15.226

Supporting Information

Synthesis of dye 15, its optical characterization and detailed information on microscopy experiments, including videos showing undisturbed cell proliferation in U2OS cells incubated with 1 µM of dye 15 for 1 h compared to untreated U2OS cells are given.

Supporting Information File 1: Experimental and analytical data, spectra, live cell imaging and assessment of cytotoxicity.
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Supporting Information File 2: Independent experiment assessing cell division of U2OS cells after treatment with 1 µM SiR dye 15.
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Supporting Information File 3: Independent experiment assessing cell division of U2OS cells after treatment with 1 µM SiR dye 15.
Format: AVI Size: 10.4 MB Download
Supporting Information File 4: Independent control experiment assessing undisturbed cell division of U2OS cells.
Format: AVI Size: 9.7 MB Download
Supporting Information File 5: Independent control experiment assessing undisturbed cell division of U2OS cells.
Format: AVI Size: 9.7 MB Download

Presentation Graphic

Picture with graphical abstract, title and authors for social media postings and presentations.

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