Stereoselective Biginelli-like reaction catalyzed by a chiral phosphoric acid bearing two hydroxy groups

Scholarly Works

• Jiang, P.-Y.; Wu, S.; Wang, J. (Joelle); Xiang, S.-H.; Tan, B. Recent advances in organocatalytic asymmetric multicomponent reactions. Organic Chemistry Frontiers 2025. doi:10.1039/d5qo00347d
• Díaz-Fernández, M.; Algarra, M.; Calvo-Losada, S.; Quirante, J.-J.; Sarabia, F.; Pino-González, M.-S. Diverse Methods with Stereoselective Induction in the Asymmetric Biginelli Reaction. Molecules (Basel, Switzerland) 2024, 29, 3864. doi:10.3390/molecules29163864
• Zhang, H.-R.; Gao, G.; Zhang, Q.; Tian, X.-C.; Yuan, W.-J.; Zhao, Z.-B.; Yan, C.-X.; Wang, J.-J.; Tu, C.-Z.; Xie, D.; Zhou, P.-P.; Yang, Z. Mechanism and origin of enantioselectivity for asymmetric Passerini reaction in the synthesis of ɑ-acyloxyamide catalyzed by chiral phosphoric acid. Molecular Catalysis 2024, 558, 114014. doi:10.1016/j.mcat.2024.114014
• Bendi, A.; Bhathiwal, A. S.; Tiwari, A.; Rao, G. B. D.; Afshari, M. Precision in stereochemistry: the integral role of catalytic asymmetric Biginelli reaction in crafting enantiomerically pure dihydropyrimidinones. Molecular diversity 2024, 28, 4441–4466. doi:10.1007/s11030-024-10827-7
• Lakhani, P.; Chodvadiya, D.; Jha, P. K.; Gupta, V. K.; Trzybiński, D.; Wozniak, K.; Kurzydłowski, K.; Goutam, U. K.; Srivastava, H.; Modi, C. K. DFT stimulation and experimental insights of chiral Cu(II)-salen scaffold within the pocket of MWW-zeolite and its catalytic study. Physical chemistry chemical physics : PCCP 2023, 25, 14374–14386. doi:10.1039/d3cp00857f
• del Corte, X.; Martínez de Marigorta, E.; Palacios, F.; Vicario, J.; Maestro, A. An overview of the applications of chiral phosphoric acid organocatalysts in enantioselective additions to CO and CN bonds. Organic Chemistry Frontiers 2022, 9, 6331–6399. doi:10.1039/d2qo01209j
• Zeng, M.; Xue, Y.; Qin, Y.; Peng, F.; Li, Q.; Zeng, M.-H. CuBr-promoted domino Biginelli reaction for the diastereoselective synthesis of bridged polyheterocycles: Mechanism studies and in vitro anti-tumor activities. Chinese Chemical Letters 2022, 33, 4891–4895. doi:10.1016/j.cclet.2022.02.075
• Sánchez-Sancho, F.; Escolano, M.; Gaviña, D.; Csáky, A. G.; Sánchez-Roselló, M.; Díaz-Oltra, S.; Del Pozo, C. Synthesis of 3,4-Dihydropyrimidin(thio)one Containing Scaffold: Biginelli-like Reactions. Pharmaceuticals (Basel, Switzerland) 2022, 15, 948. doi:10.3390/ph15080948
• Gashaw, A.; Debeli, D. K. Recent progress on asymmetric multicomponent reactions via chiral phosphoric acid catalysis. Journal of the Iranian Chemical Society 2021, 19, 1593–1611. doi:10.1007/s13738-021-02435-1
• Antenucci, A.; Dughera, S.; Renzi, P. Green Chemistry Meets Asymmetric Organocatalysis: A Critical Overview on Catalysts Synthesis. ChemSusChem 2021, 14, 2785–2853. doi:10.1002/cssc.202100573
• Hu, X.; Yin, Z.; Guo, J.; Adamson, J.; Fujiki, M.; Borovkov, V. V. Stereospecific Synthesis of Cyclic Sulfite Esters with Sulfur-Centered Chirality via Diastereoselective Strategy and Intramolecular H-Bonding Assistance. The Journal of organic chemistry 2020, 86, 379–387. doi:10.1021/acs.joc.0c02147
• Meng, D.; Xie, Y.; Peng, Q.; Wang, J. NHC-Catalyzed Enantioselective [3 + 3] Annulation to Construct 5,6-Dihydropyrimidin-4-ones. Organic letters 2020, 22, 7635–7639. doi:10.1021/acs.orglett.0c02832

Explore citations to this article at