A systems-based framework to computationally describe putative transcription factors and signaling pathways regulating glycan biosynthesis

Theodore Groth, Rudiyanto Gunawan and Sriram Neelamegham
Beilstein J. Org. Chem. 2021, 17, 1712–1724. https://doi.org/10.3762/bjoc.17.119

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Supporting Information File 1: Comparison of wet-lab studies and entries in DBs as well as Alluvial plots for all cancer types.
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Supporting Information File 2: Cistrome Cancer TF-to-glycogene subnetworks.
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Supporting Information File 3: Supplementary tables.
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A systems-based framework to computationally describe putative transcription factors and signaling pathways regulating glycan biosynthesis
Theodore Groth, Rudiyanto Gunawan and Sriram Neelamegham
Beilstein J. Org. Chem. 2021, 17, 1712–1724. https://doi.org/10.3762/bjoc.17.119

How to Cite

Groth, T.; Gunawan, R.; Neelamegham, S. Beilstein J. Org. Chem. 2021, 17, 1712–1724. doi:10.3762/bjoc.17.119

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Scholarly Works

  • Chrysinas, P.; Venkatesan, S.; Ang, I.; Ghosh, V.; Chen, C.; Neelamegham, S.; Gunawan, R. Cell and tissue-specific glycosylation pathways informed by single-cell transcriptomics. 2024. doi:10.1101/2023.09.26.559616
  • Heisterkamp, N. Glycosylation as regulator of human B-cell leukaemias in bone marrow. Frontiers in Hematology 2023, 2. doi:10.3389/frhem.2023.1279863
  • Neelamegham, S.; Zhou, Y.; Groth, T. Human GlycoEnzymes and Related Genes. Encyclopedia of Cell Biology; Elsevier, 2023; pp 452–472. doi:10.1016/b978-0-12-821618-7.00022-5
  • Groth, T.; Diehl, A. D.; Gunawan, R.; Neelamegham, S. GlycoEnzOnto: a GlycoEnzyme pathway and molecular function ontology. Bioinformatics (Oxford, England) 2022, 38, 5413–5420. doi:10.1093/bioinformatics/btac704
  • Bojar, D.; Lisacek, F. Glycoinformatics in the Artificial Intelligence Era. Chemical reviews 2022, 122, 15971–15988. doi:10.1021/acs.chemrev.2c00110
  • Stewart, N.; Wisnovsky, S. Bridging Glycomics and Genomics: New Uses of Functional Genetics in the Study of Cellular Glycosylation. Frontiers in molecular biosciences 2022, 9, 934584. doi:10.3389/fmolb.2022.934584
  • Basu, A.; Patel, N. G.; Nicholson, E. D.; Weiss, R. J. Spatiotemporal diversity and regulation of glycosaminoglycans in cell homeostasis and human disease. American journal of physiology. Cell physiology 2022, 322, C849–C864. doi:10.1152/ajpcell.00085.2022
  • Aoki-Kinoshita, K. F.; Lisacek, F.; Karlsson, N.; Kolarich, D.; Packer, N. H. GlycoBioinformatics. Beilstein journal of organic chemistry 2021, 17, 2726–2728. doi:10.3762/bjoc.17.184
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