Correction: One-pot multicomponent green Hantzsch synthesis of 1,2-dihydropyridine derivatives with antiproliferative activity

  1. Giovanna Bosica1ORCID Logo,
  2. Kaylie Demanuele1,
  3. José M. Padrón2ORCID Logo and
  4. Adrián Puerta2ORCID Logo

1Department of Chemistry, University of Malta, Msida, MSD 2080 Malta
2BioLab, Instituto Universitario de Bio-Orgánica “Antonio González” (IUBO-AG), Universidad de La Laguna, c/Astrofísico Francisco Sánchez 2, 38206 La Laguna, Spain

  1. Corresponding author email

Associate Editor: L. Vaccaro
Beilstein J. Org. Chem. 2021, 17, 2026–2027.
Received 16 Jul 2021, Accepted 29 Jul 2021, Published 10 Aug 2021

Keywords: antiproliferative activity; 1,2-dihydropyridines; green Hantzsch synthesis; heterogeneous catalysis; one-pot multicomponent reaction

The authors noticed that the E-factor (E) was calculated using a wrong Equation 2 in the original publication:

[Graphic 1]

The correct Equation 2 should be the following:

[Graphic 2]

Accordingly, the Conclusion section should be amended with the following sentence:

A high AE of 74% and a low E-factor of 0.43 highlight the green character of the procedure.

The authors apologize for any inconvenience caused by the originally published wrong Equation 2.

© 2021 Bosica et al.; licensee Beilstein-Institut.
This is an Open Access article under the terms of the Creative Commons Attribution License ( Please note that the reuse, redistribution and reproduction in particular requires that the author(s) and source are credited and that individual graphics may be subject to special legal provisions.
The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (

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