Supporting Information
| Supporting Information File 1: Amino acid sequence alignment, details about the mutagenesis, purification and analytical data. | ||
| Format: PDF | Size: 2.5 MB | Download |
Cite the Following Article
Targeting active site residues and structural anchoring positions in terpene synthases
Anwei Hou and Jeroen S. Dickschat
Beilstein J. Org. Chem. 2021, 17, 2441–2449.
https://doi.org/10.3762/bjoc.17.161
How to Cite
Hou, A.; Dickschat, J. S. Beilstein J. Org. Chem. 2021, 17, 2441–2449. doi:10.3762/bjoc.17.161
Download Citation
Citation data can be downloaded as file using the "Download" button or used for copy/paste from the text window
below.
Citation data in RIS format can be imported by all major citation management software, including EndNote,
ProCite, RefWorks, and Zotero.
Presentation Graphic
| Picture with graphical abstract, title and authors for social media postings and presentations. | ||
| Format: PNG | Size: 10.3 MB | Download |
Citations to This Article
Up to 20 of the most recent references are displayed here.
Scholarly Works
- Li, H.; Bai, Z.; Tabekoueng, G. B.; Xing, B.; Goldfuss, B.; Ma, M.; Yang, D.; Dickschat, J. S. A Hydrophobic Tunnel and a Gatekeeper at the Active Site Entrance in Two Type I Terpene Synthases. ACS Catalysis 2025, 15, 6209–6215. doi:10.1021/acscatal.5c01540
- Zhou, J.; Huang, M. Navigating the landscape of enzyme design: from molecular simulations to machine learning. Chemical Society reviews 2024, 53, 8202–8239. doi:10.1039/d4cs00196f
- Yang, X.; Gao, Q.; Zheng, X. Microbial Isoprenoids as Drop-In Biofuel. Biofuel and Biorefinery Technologies; Springer Nature Switzerland, 2024; pp 245–287. doi:10.1007/978-3-031-61637-2_9
- Huang, Z.-Y.; Taizoumbe, K. A.; Liang, C.; Goldfuss, B.; Xu, J.-H.; Dickschat, J. S. Spiroluchuene A Synthase: A Cyclase from Aspergillus luchuensis Forming a Spirotetracyclic Diterpene. Angewandte Chemie (International ed. in English) 2023, 62, e202315659. doi:10.1002/anie.202315659
- Huang, Z.; Taizoumbe, K. A.; Liang, C.; Goldfuss, B.; Xu, J.; Dickschat, J. S. Spiroluchuen A‐Synthase: Eine Cyclase ausAspergillus luchuensis, die ein spirotetracyclisches Diterpen bildet. Angewandte Chemie 2023, 135. doi:10.1002/ange.202315659
- Xu, H.; Dickschat, J. S. Turning a Sesquiterpene Synthase into a Di- and Sesterterpene Synthase. ACS Catalysis 2023, 13, 12723–12729. doi:10.1021/acscatal.3c03740
- Li, Z.; Zhang, L.; Xu, K.; Jiang, Y.; Du, J.; Zhang, X.; Meng, L.-H.; Wu, Q.; Du, L.; Li, X.; Hu, Y.; Xie, Z.; Jiang, X.; Tang, Y.-J.; Wu, R.; Guo, R.-T.; Li, S. Molecular insights into the catalytic promiscuity of a bacterial diterpene synthase. Nature communications 2023, 14, 4001. doi:10.1038/s41467-023-39706-9
- Liu, Y.; Chen, X.; Zhang, C. Sustainable biosynthesis of valuable diterpenes in microbes. Engineering microbiology 2022, 3, 100058. doi:10.1016/j.engmic.2022.100058
- Yan, X.; Zhou, J.; Ge, J.; Li, W.; Liang, D.; Singh, W.; Black, G.; Nie, S.; Liu, J.; Sun, M.; Qiao, J.; Huang, M. Computer-Informed Engineering: A New Class I Sesquiterpene Synthase JeSTS4 for the Synthesis of an Unusual C10-(S)-Bicyclogermacrene. ACS Catalysis 2022, 12, 4037–4045. doi:10.1021/acscatal.2c00013
- Xu, H.; Dickschat, J. S. Mechanistic Investigations on Microbial Type I Terpene Synthases through Site-directed Mutagenesis. Synthesis 2021, 54, 1551–1565. doi:10.1055/a-1675-8208
