Cryogels: recent applications in 3D-bioprinting, injectable cryogels, drug delivery, and wound healing

Luke O. Jones, Leah Williams, Tasmin Boam, Martin Kalmet, Chidubem Oguike and Fiona L. Hatton
Beilstein J. Org. Chem. 2021, 17, 2553–2569.

Cite the Following Article

Cryogels: recent applications in 3D-bioprinting, injectable cryogels, drug delivery, and wound healing
Luke O. Jones, Leah Williams, Tasmin Boam, Martin Kalmet, Chidubem Oguike and Fiona L. Hatton
Beilstein J. Org. Chem. 2021, 17, 2553–2569.

How to Cite

Jones, L. O.; Williams, L.; Boam, T.; Kalmet, M.; Oguike, C.; Hatton, F. L. Beilstein J. Org. Chem. 2021, 17, 2553–2569. doi:10.3762/bjoc.17.171

Download Citation

Citation data can be downloaded as file using the "Download" button or used for copy/paste from the text window below.
Citation data in RIS format can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Zotero.

Presentation Graphic

Picture with graphical abstract, title and authors for social media postings and presentations.
Format: PNG Size: 9.2 MB Download

Citations to This Article

Up to 20 of the most recent references are displayed here.

Scholarly Works

  • Engel, N.; Hoffmann, T.; Behrendt, F.; Liebing, P.; Weber, C.; Gottschaldt, M.; Schubert, U. S. Cryogels Based on Poly(2-oxazoline)s through Development of Bi- and Trifunctional Cross-Linkers Incorporating End Groups with Adjustable Stability. Macromolecules 2024, 57, 2915–2927. doi:10.1021/acs.macromol.3c02030
  • Abdi, G.; Jain, M.; Patil, N.; Tariq, M.; Choudhary, S.; Kumar, P.; Raj, N. S.; Mohsen Ali, S. S.; Uthappa, U. T. Tragacanth gum-based hydrogels for drug delivery and tissue engineering applications. Frontiers in Materials 2024, 11. doi:10.3389/fmats.2024.1296399
  • Canatar, İ.; Özdaş, S.; Baydemir Peşint, G. Phyllanthus emblica‐Loaded Cryogels for Improved Wound Care: Characterization and In Vitro Studies. Macromolecular Materials and Engineering 2024. doi:10.1002/mame.202300404
  • Doser, G.; Su, E.; Okay, O. Effects of cryogenic condition and chemistry on the properties of synthetic and biopolymer cryogels. Reactive and Functional Polymers 2023, 190, 105635. doi:10.1016/j.reactfunctpolym.2023.105635
  • Bilici, Ç.; Altunbek, M.; Afghah, F.; Tatar, A. G.; Koç, B. Embedded 3D Printing of Cryogel-Based Scaffolds. ACS biomaterials science & engineering 2023, 9, 5028–5038. doi:10.1021/acsbiomaterials.3c00751
  • Zagni, C.; Coco, A.; Mecca, T.; Curcuruto, G.; Patamia, V.; Mangano, K.; Rescifina, A.; Carroccio, S. C. Sponge-like macroporous cyclodextrin-based cryogels for controlled drug delivery. Materials Chemistry Frontiers 2023, 7, 2693–2705. doi:10.1039/d3qm00139c
  • Kudaibergen, G.; Akhmetkarimova, Z.; Yildirim, E.; Baidarbekov, M. Thiol-ene clickable gelatin–hyaluronic acid cryogels. Journal of Materials Science 2023, 58, 10821–10831. doi:10.1007/s10853-023-08693-z
  • Demir, D.; Goksen, G.; Ceylan, S.; Trif, M.; Rusu, A. V. Optimized Peppermint Essential Oil Microcapsules Loaded into Gelatin-Based Cryogels with Enhanced Antimicrobial Activity. Polymers 2023, 15, 2782. doi:10.3390/polym15132782
  • Dumitru, M. V.; Sandu, T.; Miron, A.; Zaharia, A.; Radu, I. C.; Gavrilă, A.-M.; Sârbu, A.; Iovu, H.; Chiriac, A.-L.; Iordache, T. V. Hybrid Cryogels with Superabsorbent Properties as Promising Materials for Penicillin G Retention. Gels (Basel, Switzerland) 2023, 9, 443. doi:10.3390/gels9060443
  • Dragan, E. S.; Ghiorghita, C. A.; Dinu, M. V.; Duceac, I. A.; Coseri, S. Fabrication of self-antibacterial chitosan/oxidized starch polyelectrolyte complex sponges for controlled delivery of curcumin. Food Hydrocolloids 2023, 135, 108147. doi:10.1016/j.foodhyd.2022.108147
  • Mukasheva, F.; Moazzam, M.; Yernaimanova, B.; Shehzad, A.; Zhanbassynova, A.; Berillo, D.; Akilbekova, D. 3d Printed Hydrogel Scaffold with Gradient Structure for Improved Stem Cells Osteodifferentiation. Elsevier BV 2023. doi:10.2139/ssrn.4536366
  • Mao, S.; Man, J.; Wang, J.; Fu, L.; Yin, C.; Karimi-Maleh, H. Research progress and challenges of bioprinting in wound dressing and healing: Bibliometrics-based analysis and perspectives. International journal of bioprinting 2022, 9, 653. doi:10.18063/ijb.v9i2.653
  • Moazzam, M.; Shehzad, A.; Sultanova, D.; Mukasheva, F.; Trifonov, A.; Berillo, D.; Akilbekova, D. Macroporous 3D printed structures for regenerative medicine applications. Bioprinting 2022, 28, e00254. doi:10.1016/j.bprint.2022.e00254
  • Hajizadeh, S.; Dicko, C.; Bülow, L. Interaction of haemin with albumin-based macroporous cryogel: Adsorption isotherm and fluorescence quenching studies. Frontiers in bioengineering and biotechnology 2022, 10, 1072153. doi:10.3389/fbioe.2022.1072153
  • Akin, B.; Ozmen, M. M. Antimicrobial cryogel dressings towards effective wound healing. Progress in biomaterials 2022, 11, 331–346. doi:10.1007/s40204-022-00202-w
  • Kudaibergen, G.; Zhunussova, M.; Mun, E. A.; Ramankulov, Y.; Ogay, V. Macroporous Cell-Laden Gelatin/Hyaluronic Acid/Chondroitin Sulfate Cryogels for Engineered Tissue Constructs. Gels (Basel, Switzerland) 2022, 8, 590. doi:10.3390/gels8090590
  • Mashabela, L. T.; Maboa, M. M.; Miya, N. F.; Ajayi, T. O.; Chasara, R. S.; Milne, M.; Mokhele, S.; Demana, P. H.; Witika, B. A.; Siwe-Noundou, X.; Poka, M. S. A Comprehensive Review of Cross-Linked Gels as Vehicles for Drug Delivery to Treat Central Nervous System Disorders. Gels (Basel, Switzerland) 2022, 8, 563. doi:10.3390/gels8090563
  • El-Naggar, M. E.; Gaballah, S.; Abdel-Maksoud, G.; El-Sayed, H. S.; Youssef, A. M. Preparation of bactericidal zinc oxide nanoparticles loaded carboxymethyl cellulose/polyethylene glycol cryogel for gap filling of archaeological bones. Journal of Materials Research and Technology 2022, 20, 114–127. doi:10.1016/j.jmrt.2022.07.013
  • Grigoriev, A. M.; Basok, Y. B.; Kirillova, A. D.; Surguchenko, V. A.; Shmerko, N. P.; Kulakova, V. K.; Ivanov, R. V.; Lozinsky, V. I.; Subbot, A. M.; Sevastianov, V. I. Cryogenically structured gelatin-based hydrogel as a resorbable macroporous matrix for biomedical technologies. Russian Journal of Transplantology and Artificial Organs 2022, 24, 83–93. doi:10.15825/1995-1191-2022-2-83-93
  • Tyshkunova, I. V.; Poshina, D. N.; Skorik, Y. A. Cellulose Cryogels as Promising Materials for Biomedical Applications. International journal of molecular sciences 2022, 23, 2037. doi:10.3390/ijms23042037
Other Beilstein-Institut Open Science Activities