Cite the Following Article
Biochemistry of fluoroprolines: the prospect of making fluorine a bioelement
Vladimir Kubyshkin, Rebecca Davis and Nediljko Budisa
Beilstein J. Org. Chem. 2021, 17, 439–460.
https://doi.org/10.3762/bjoc.17.40
How to Cite
Kubyshkin, V.; Davis, R.; Budisa, N. Beilstein J. Org. Chem. 2021, 17, 439–460. doi:10.3762/bjoc.17.40
Download Citation
Citation data can be downloaded as file using the "Download" button or used for copy/paste from the text window
below.
Citation data in RIS format can be imported by all major citation management software, including EndNote,
ProCite, RefWorks, and Zotero.
Presentation Graphic
| Picture with graphical abstract, title and authors for social media postings and presentations. | ||
| Format: PNG | Size: 8.9 MB | Download |
Citations to This Article
Up to 20 of the most recent references are displayed here.
Scholarly Works
- Kaźmierczak, M.; Siodła, T.; Bilska‐Markowska, M. Regioselective Addition of Organolithium Reagents to Fluorinated Proline Amides: Insights from Experiment and Theory. ChemistrySelect 2025, 10. doi:10.1002/slct.202505278
- Chen, J.; You, C.; Xie, H.; Zhu, Q. Mitochondrial RNA in Inflammation. International journal of biological sciences 2025, 21, 5378–5392. doi:10.7150/ijbs.119841
- Zhu, Z.; Xu, Y.; Kyriazakos, S.; Prakash, G. K. S. Nucleophilic Trifluoromethoxylation of Benzyl Bromides via Carbonyl Diimidazole. European Journal of Organic Chemistry 2025, 28. doi:10.1002/ejoc.202500529
- Oikawa, Y.; Uzawa, T.; Berenger, F.; Minagawa, N.; Yumoto, A.; Takaku, H.; Tamura, R.; Ito, Y.; Tsuda, K. GPepT: A Foundation Language Model for Peptidomimetics Incorporating Noncanonical Amino Acids. ACS medicinal chemistry letters 2025, 16, 1670. doi:10.1021/acsmedchemlett.5c00375
- Ryan, P.; Bhattacherjee, D.; Wirth, T.; Hunter, L.; Pascali, G. Electrochemical Fluorination of Proline Derivatives. European Journal of Organic Chemistry 2025, 28. doi:10.1002/ejoc.202500264
- Iesu, L.; Sai, M.; Torbeev, V.; Kieffer, B.; Pelta, J.; Cressiot, B. Single-molecule nanopore sensing of proline cis/trans amide isomers. Chemical science 2025, 16, 9730–9738. doi:10.1039/d5sc01156f
- Marin, Ž.; Lacombe, C.; Rostami, S.; Arasteh Kani, A.; Borgonovo, A.; Cserjan-Puschmann, M.; Mairhofer, J.; Striedner, G.; Wiltschi, B. Residue-Specific Incorporation of Noncanonical Amino Acids in Auxotrophic Hosts: Quo Vadis?. Chemical reviews 2025, 125, 4840–4932. doi:10.1021/acs.chemrev.4c00280
- Ryan, P.; Iftikhar, R.; Hunter, L. Origami with small molecules: exploiting the C-F bond as a conformational tool. Beilstein journal of organic chemistry 2025, 21, 680–716. doi:10.3762/bjoc.21.54
- Elena-Real, C. A.; Urbanek, A.; Sagar, A.; Mohanty, P.; Levy, G.; Morató, A.; Fournet, A.; Allemand, F.; Sibille, N.; Mittal, J.; Sinnaeve, D.; Bernadó, P. Site-Specific Incorporation of Fluorinated Prolines into Proteins and Their Impact on Neighbouring Residues. Chemistry (Weinheim an der Bergstrasse, Germany) 2024, 31, e202403718. doi:10.1002/chem.202403718
- Kubyshkin, V.; Mykhailiuk, P. K. Proline Analogues in Drug Design: Current Trends and Future Prospects. Journal of medicinal chemistry 2024, 67, 20022–20055. doi:10.1021/acs.jmedchem.4c01987
- Karbalaei-Heidari, H. R.; Budisa, N. Advanced and Safe Synthetic Microbial Chassis with Orthogonal Translation System Integration. ACS synthetic biology 2024, 13, 2992–3002. doi:10.1021/acssynbio.4c00437
- Kubyshkin, V.; Rubini, M. Proline Analogues. Chemical reviews 2024, 124, 8130–8232. doi:10.1021/acs.chemrev.4c00007
- Nieto-Domínguez, M.; Sako, A.; Enemark-Rasmussen, K.; Gotfredsen, C. H.; Rago, D.; Nikel, P. I. Enzymatic synthesis of mono- and trifluorinated alanine enantiomers expands the scope of fluorine biocatalysis. Communications chemistry 2024, 7, 104. doi:10.1038/s42004-024-01188-1
- Ganguly, H. K.; Ludwig, B. A.; Tressler, C. M.; Bhatt, M. R.; Pandey, A. K.; Quinn, C. M.; Bai, S.; Yap, G. P. A.; Zondlo, N. J. 4,4-Difluoroproline as a Unique 19F NMR Probe of Proline Conformation. Biochemistry 2024, 63, 1131–1146. doi:10.1021/acs.biochem.3c00697
- Loughlin, J. O.; Zinovjev, K.; Napolitano, S.; van der Kamp, M.; Rubini, M. 4-Thiaproline accelerates the slow folding phase of proteins containing cis prolines in the native state by two orders of magnitude. Protein science : a publication of the Protein Society 2024, 33, e4877. doi:10.1002/pro.4877
- Nieto-Dominguez, M.; Sako, A.; Enemark-Rasmussen, K.; Gotfredsen, C. H.; Rago, D.; Nikel, P. I. High-yield enzymatic synthesis of mono– and trifluorinated alanine enantiomers. Cold Spring Harbor Laboratory 2023. doi:10.1101/2023.11.28.569005
- Karbalaei-Heidari, H. R.; Budisa, N. Genomically integrated orthogonal translation inEscherichia coli, a new synthetic auxotrophic chassis with altered genetic code, genetic firewall, and enhanced protein expression. Cold Spring Harbor Laboratory 2023. doi:10.1101/2023.11.18.567690
- Goettig, P.; Koch, N. G.; Budisa, N. Non-Canonical Amino Acids in Analyses of Protease Structure and Function. International journal of molecular sciences 2023, 24, 14035. doi:10.3390/ijms241814035
- Miles, S. A.; Nillama, J. A.; Hunter, L. Tinker, Tailor, Soldier, Spy: The Diverse Roles That Fluorine Can Play within Amino Acid Side Chains. Molecules (Basel, Switzerland) 2023, 28, 6192. doi:10.3390/molecules28176192
- O' Loughlin, J.; Zinovjev, K.; Napolitano, S.; van der Kamp, M.; Rubini, M. 4-Thiaproline accelerates the slow folding phase of proteins containingcisprolines in the native state by two orders of magnitude. Cold Spring Harbor Laboratory 2023. doi:10.1101/2023.06.23.546227