Menthyl esterification allows chiral resolution for the synthesis of artificial glutamate analogs

Kenji Morokuma, Shuntaro Tsukamoto, Kyosuke Mori, Kei Miyako, Ryuichi Sakai, Raku Irie and Masato Oikawa
Beilstein J. Org. Chem. 2021, 17, 540–550. https://doi.org/10.3762/bjoc.17.48

Supporting Information

Supporting Information File 1: Synthetic procedures.
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Supporting Information File 2: NMR spectra of all new compounds.
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Supporting Information File 3: X-ray structure of the menthyl ester 10.
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Supporting Information File 4: CIF file for the X-ray structure of the menthyl ester 10.
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Supporting Information File 5: Stereo diagrams for 10, 21*, and 21 as well as superimposed structures of the stable conformers of 10*.
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Supporting Information File 6: Assignments and intensities of all NOESY crosspeaks observed for 10*, 10, 21*, and 21.
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Supporting Information File 7: Stereochemical analysis of TKM-38 by the PGME amide method, as a support for the original determination of the configuration of menthyl esters 21 and 21* based on NOESY spectra and CONFLEX calculations.
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Cite the Following Article

Menthyl esterification allows chiral resolution for the synthesis of artificial glutamate analogs
Kenji Morokuma, Shuntaro Tsukamoto, Kyosuke Mori, Kei Miyako, Ryuichi Sakai, Raku Irie and Masato Oikawa
Beilstein J. Org. Chem. 2021, 17, 540–550. https://doi.org/10.3762/bjoc.17.48

How to Cite

Morokuma, K.; Tsukamoto, S.; Mori, K.; Miyako, K.; Sakai, R.; Irie, R.; Oikawa, M. Beilstein J. Org. Chem. 2021, 17, 540–550. doi:10.3762/bjoc.17.48

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