The Groebke–Blackburn–Bienaymé reaction in its maturity: innovation and improvements since its 21st birthday (2019–2023)

Cristina Martini, Muhammad Idham Darussalam Mardjan and Andrea Basso
Beilstein J. Org. Chem. 2024, 20, 1839–1879. https://doi.org/10.3762/bjoc.20.162

Chemical Information

Calculated using the Chemistry Development Kit 2.12
Molecular Formula C10H8O2
Molecular Weight 160.17 g/mol
Exact Mass 160.0524 Da
InChI
InChI=1S/C10H8O2/c1-2-7-12-10-5-3-9(8-11)4-6-10/h1,3-6,8H,7H2
InChIKey
GSSBOYWRKTVVQX-UHFFFAOYSA-N
SMILES
C#CCOC1=CC=C(C=C1)C=O
Number of Atoms 20
Number of H-Bond Acceptors 2
Number of H-Bond Donors 0
Atoms in the Largest π-System 9
XLogP 0.9
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