The Groebke–Blackburn–Bienaymé reaction in its maturity: innovation and improvements since its 21st birthday (2019–2023)

Cristina Martini, Muhammad Idham Darussalam Mardjan and Andrea Basso
Beilstein J. Org. Chem. 2024, 20, 1839–1879. https://doi.org/10.3762/bjoc.20.162

Chemical Information

Calculated using the Chemistry Development Kit 2.12
Molecular Formula C5H5ClN2
Molecular Weight 128.56 g/mol
Exact Mass 128.0141 Da
InChI
InChI=1S/C5H5ClN2/c6-4-1-2-5(7)8-3-4/h1-3H,(H2,7,8)
InChIKey
MAXBVGJEFDMHNV-UHFFFAOYSA-N
SMILES
C1=C(C=NC(=C1)N)Cl
Number of Atoms 13
Number of H-Bond Acceptors 2
Number of H-Bond Donors 1
Atoms in the Largest π-System 7
XLogP 0.0
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