Preparation of spirocyclic oxindoles by cyclisation of an oxime to a nitrone and dipolar cycloaddition
Beth L. Ritchie, Alexandra Longcake and Iain Coldham
Beilstein J. Org. Chem. 2025, 21, 1890–1896.
https://doi.org/10.3762/bjoc.21.146
Chemical Information
Calculated using the Chemistry Development Kit 2.12
| Molecular Formula | C16H18N2O2 |
| Molecular Weight | 270.33 g/mol |
| Exact Mass | 270.1368 Da |
| InChI |
InChI=1S/C16H18N2O2/c1-3-4-9-14-16(10-11-18(14)20)12-7-5-6-8-13(12)17(2)15(16)19/h3,5-8,11,14H,1,4,9-10H2,2H3
|
| InChIKey |
FVSLPVYMXGHHHD-UHFFFAOYSA-N
|
| SMILES |
C=CCCC1C2(CC=[N+]1[O-])C3=C(C=CC=C3)N(C)C2=O
|
| Number of Atoms | 38 |
| Number of H-Bond Acceptors | 2 |
| Number of H-Bond Donors | 0 |
| Atoms in the Largest π-System | 9 |
| XLogP | 1.1 |
