Preparation of spirocyclic oxindoles by cyclisation of an oxime to a nitrone and dipolar cycloaddition
Beth L. Ritchie, Alexandra Longcake and Iain Coldham
Beilstein J. Org. Chem. 2025, 21, 1890–1896.
https://doi.org/10.3762/bjoc.21.146
Chemical Information
Calculated using the Chemistry Development Kit 2.12
| Molecular Formula | C17H17N3O4 |
| Molecular Weight | 327.34 g/mol |
| Exact Mass | 327.1219 Da |
| InChI |
InChI=1S/C17H17N3O4/c1-18-10-6-4-3-5-9(10)17(16(18)23)7-11-12-13(24-20(11)8-17)15(22)19(2)14(12)21/h3-6,11-13H,7-8H2,1-2H3/t11-,12-,13+,17+/m1/s1
|
| InChIKey |
KDCFXNDIODHFAG-FJZAXULXSA-N
|
| SMILES |
CN1C2=C(C=CC=C2)[C@@]3(C[C@]4([H])[C@]5([H])[C@@]([H])(C(=O)N(C)C5=O)ON4C3)C1=O
|
| Number of Atoms | 41 |
| Number of H-Bond Acceptors | 5 |
| Number of H-Bond Donors | 0 |
| Atoms in the Largest π-System | 9 |
| XLogP | -1.4 |
